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NCT05878236 · ClinicalTrials.gov registry record

iMmune SignAtures and Clinical outComes in AP

A clinical trial of Acute Pancreatitis, sponsored by Ohio State University.

Recruiting
Registry status
198
Enrollment target
5
Study locations

NCT05878236 is a study of Acute Pancreatitis that is actively recruiting participants, run by Ohio State University. The registered enrollment target is 198 participants, below the 2,299-participant average among 10 other Acute Pancreatitis trials with a reported enrollment target (91% lower). The trial reports 5 study locations across 5 states.

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The verdict

NCT05878236, a study of Acute Pancreatitis, is actively recruiting participants, sponsored by Ohio State University.

RECRUITING
Registry status
198 participants
Enrollment target
5
Study locations

Study Summary

The MoSAIC study is a prospective, observational study designed to develop an early prediction tool for severe acute pancreatitis (SAP) and define a distinct immunologic profile compared to moderate acute pancreatitis (MAP). The aims are to validate a new multi-cytokine panel for early prediction of SAP and to identify the specific immune cells that correspond with cytokine signatures in early acute pancreatitis to characterize the immune pathways driving the development of SAP. Participants will provide blood samples and complete patient surveys and interviews within 36 hours of hospital presentation, at 48 hours, and hospital day 7 (if admitted). Data on hospital stay, medical history, clinical course, and severity of disease will be collected.

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST CyTOF Analysis

Study Locations (5)

California

  • University of Southern California - Los Angeles

Illinois

  • University of Illinois Chicago - Chicago

Ohio

  • The Ohio State University - Columbus

Pennsylvania

  • University of Pittsburgh - Pittsburgh

Washington

  • Benaroya Research Institute - Seattle

Trial Details

FieldValue
Enrollment Target 198 participants
Start Date 2023-03-06
Est. Completion 2027-12-31

Sponsor

Ohio State University

552 total trials

What the Registry Record Tells You About NCT05878236

The ClinicalTrials.gov registry entry for NCT05878236 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 198 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,299-participant average among 10 other Acute Pancreatitis trials with a reported enrollment target (91% lower). The listed sponsor is Ohio State University, which has 552 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Acute Pancreatitis appearing as the primary indexed condition, and to 1 intervention - of which CyTOF Analysis is the first listed.

NCT05878236 reports 5 study locations spanning 5 distinct geographic areas - top geographies include California, Illinois, Ohio.

Frequently Asked Questions

What is clinical trial NCT05878236 about?

NCT05878236 is a clinical study titled "iMmune SignAtures and Clinical outComes in AP". The MoSAIC study is a prospective, observational study designed to develop an early prediction tool for severe acute pancreatitis (SAP) and define a distinct immunologic profile compared to moderate acute pancreatitis (MAP). The aims are to validate a new multi-cytokine panel for early prediction of...

What is the current status of trial NCT05878236?

This trial is currently recruiting. The enrollment target is 198 participants. The study started on 2023-03-06. Estimated completion is 2027-12-31.

What conditions does trial NCT05878236 study?

This clinical trial studies the following conditions: Acute Pancreatitis.

What interventions are being tested in trial NCT05878236?

The interventions under investigation include: CyTOF Analysis (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT05878236?

This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05878236 being conducted?

This trial has 5 study locations across California, Illinois, Ohio, Pennsylvania, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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