Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05862558 · ClinicalTrials.gov registry record

Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR

A clinical trial of Aortic Valve Stenosis and Iliac Disease, sponsored by Baylor Research Institute.

Recruiting
Registry status
50
Enrollment target
1
Study location

NCT05862558: Recruiting study of Aortic Valve Stenosis and Iliac Disease, sponsored by Baylor Research Institute.

NCT05862558 is a study of Aortic Valve Stenosis and Iliac Disease that is actively recruiting participants, run by Baylor Research Institute. The registered enrollment target is 50 participants, below the 1,042-participant average among 30 other Aortic Valve Stenosis trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05862558, a study of Aortic Valve Stenosis and Iliac Disease, is actively recruiting participants, sponsored by Baylor Research Institute.

RECRUITING
Registry status
50 participants
Enrollment target
1
Study location

Study Summary

To assess the efficacy and safety of Intravascular Lithotripsy (IVL) in subjects undergoing transfemoral TAVR in patients with severe iliac disease, prohibitive for transfemoral TAVR in patients with severe symptomatic aortic stenosis, otherwise considered for alternative access TAVR. (e.g. trans-carotid)

Primary Outcome

Defined as final residual stenosis ≤30% without flow-limiting dissection (≥ Grade D) of the lesion

Conditions Studied

Aortic Valve Stenosis Iliac Disease

Interventions

  • DEVICE Shockwave Balloon

Study Locations (1)

Texas

  • Baylor Scott and White Heart Hospital - Plano

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2023-03-30
Est. Completion 2026-06-01
Baylor Research Institute

180 total trials

What NCT05862558 shows while recruiting

NCT05862558 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,042-participant average among 30 other Aortic Valve Stenosis trials with a reported enrollment target (95% lower).

The record links to 2 conditions, with Aortic Valve Stenosis appearing as the primary indexed condition, and to 1 intervention - of which Shockwave Balloon is the first listed.

NCT05862558 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05862558 about?

NCT05862558 is a clinical study titled "Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR". To assess the efficacy and safety of Intravascular Lithotripsy (IVL) in subjects undergoing transfemoral TAVR in patients with severe iliac disease, prohibitive for transfemoral TAVR in patients with severe symptomatic aortic stenosis, otherwise considered for alternative access TAVR. (e.g. trans-ca...

What is the current status of trial NCT05862558?

This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2023-03-30. Estimated completion is 2026-06-01.

What conditions does trial NCT05862558 study?

This clinical trial studies the following conditions: Aortic Valve Stenosis, Iliac Disease.

What interventions are being tested in trial NCT05862558?

The interventions under investigation include: Shockwave Balloon (DEVICE).

Who is sponsoring clinical trial NCT05862558?

This trial is sponsored by Baylor Research Institute, which has 180 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05862558 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Aortic Valve Stenosis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05862558's enrollment target sits among peer trials

50 25th of 30 higher than 6 of 30 other Aortic Valve Stenosis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Aortic Valve Stenosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00200889 · 50 participants · Early Phase 1

    Mapping Auricular Vagus Nerve Circuitry

  • NCT00409435 · 50 participants · Phase 2

    A Study of Pyridostigmine in Postural Tachycardia Syndrome

  • NCT01202305 · 50 participants

    The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies

  • NCT01225913 · 50 participants · Phase 4

    Mechanism(s) of Airflow Limitation During Exacerbation of Asthma

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

More recruiting context for NCT05862558

Source: ClinicalTrials.gov NCT05862558, the US trial registry maintained by the National Library of Medicine. NCT05862558 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.