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NCT05859490 · ClinicalTrials.gov registry record · Phase 1
Immunogenicity of Yellow Fever Vaccine 17D in Adults With Prior 17D Vaccination
A Phase 1 study of Immunization; Infection and Yellow Fever, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 35
- Enrollment target
- 1
- Study location
NCT05859490 is a Phase 1 study of Immunization; Infection and Yellow Fever that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 35 participants, below the 270-participant average among 4 other Immunization; Infection trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05859490, a Phase 1 study of Immunization; Infection and Yellow Fever, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to assess the immune response to the yellow fever vaccine 17D in adults with prior 17D vaccination. The main questions this study aims to answer are: * how does prior vaccination affect antibody responses to re-vaccination? * how does prior vaccination affect the immune cell response to re-vaccination? Participants will: * have been previously vaccinated with 17D. * be re-vaccinated with 17D. * provide medical and travel histories. * provide a blood sample prior to vaccination * provide a blood sample approximately every other day for 14 days after vaccination. * provide a blood sample approximately 28 days after vaccination. * complete a daily diary of symptoms following vaccination for 14 days. * report any additional symptoms after 14 days.
Conditions Studied
Interventions
- BIOLOGICAL 17D
Study Locations (1)
Oregon
- Oregon Health & Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2023-08-01 |
| Est. Completion | 2025-12-31 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05859490
The ClinicalTrials.gov registry entry for NCT05859490 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 270-participant average among 4 other Immunization; Infection trials with a reported enrollment target (87% lower). The listed sponsor is Oregon Health and Science University, which has 546 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Immunization; Infection appearing as the primary indexed condition, and to 1 intervention - of which 17D is the first listed.
NCT05859490 reports 1 study location spanning 1 distinct geographic area - top geographies include Oregon.
Frequently Asked Questions
What is clinical trial NCT05859490 about?
NCT05859490 is a clinical study titled "Immunogenicity of Yellow Fever Vaccine 17D in Adults With Prior 17D Vaccination". The goal of this clinical trial is to assess the immune response to the yellow fever vaccine 17D in adults with prior 17D vaccination. The main questions this study aims to answer are: * how does prior vaccination affect antibody responses to re-vaccination? * how does prior vaccination affect the ...
What is the current status of trial NCT05859490?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 35 participants. The study started on 2023-08-01. Estimated completion is 2025-12-31.
What conditions does trial NCT05859490 study?
This clinical trial studies the following conditions: Immunization; Infection, Yellow Fever.
What interventions are being tested in trial NCT05859490?
The interventions under investigation include: 17D (BIOLOGICAL).
Who is sponsoring clinical trial NCT05859490?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05859490 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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