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NCT05809752 · ClinicalTrials.gov registry record · Phase 1

A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)

A Phase 1 study of Triple Negative Breast Cancer and HER2-positive Breast Cancer, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Recruiting
Registry status
Phase 1
Development phase
18
Enrollment target
3
Study locations

NCT05809752 is a Phase 1 study of Triple Negative Breast Cancer and HER2-positive Breast Cancer that is actively recruiting participants, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 18 participants, below the 246-participant average among 118 other Triple Negative Breast Cancer trials with a reported enrollment target (93% lower). The trial reports 3 study locations across 2 states.

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The verdict

NCT05809752, a Phase 1 study of Triple Negative Breast Cancer and HER2-positive Breast Cancer, is actively recruiting participants, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

RECRUITING
Registry status
Phase 1
Development phase
18 participants
Enrollment target
3
Study locations

Study Summary

The purpose of this study is to learn about the effects of the study treatment, Dendritic Cell Vaccine (DCV), to find the highest dose of the study treatment that can be given safely to Breast Cancer patients with Leptomeningeal Disease

Interventions

  • BIOLOGICAL Dendritic Cell Vaccine

Study Locations (3)

New York

  • Roswell Park Comprehensive Cancer Center - Buffalo
  • Memorial Sloan Kettering Cancer Center - New York

Florida

  • Moffitt Cancer Center - Tampa

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2023-08-22
Est. Completion 2026-03
Phase Phase 1

What the Registry Record Tells You About NCT05809752

The ClinicalTrials.gov registry entry for NCT05809752 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 246-participant average among 118 other Triple Negative Breast Cancer trials with a reported enrollment target (93% lower). The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Triple Negative Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Dendritic Cell Vaccine is the first listed.

NCT05809752 reports 3 study locations spanning 2 distinct geographic areas - top geographies include New York, Florida.

Frequently Asked Questions

What is clinical trial NCT05809752 about?

NCT05809752 is a clinical study titled "A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)". The purpose of this study is to learn about the effects of the study treatment, Dendritic Cell Vaccine (DCV), to find the highest dose of the study treatment that can be given safely to Breast Cancer patients with Leptomeningeal Disease

What is the current status of trial NCT05809752?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2023-08-22. Estimated completion is 2026-03.

What conditions does trial NCT05809752 study?

This clinical trial studies the following conditions: Triple Negative Breast Cancer, HER2-positive Breast Cancer, Leptomeningeal Disease.

What interventions are being tested in trial NCT05809752?

The interventions under investigation include: Dendritic Cell Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT05809752?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05809752 being conducted?

This trial has 3 study locations across Florida, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.