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NCT05794087 · ClinicalTrials.gov registry record · NA
The Role of Macrophage Activation in Lung Injury Following Ozone Exposure
A NA study of Air Pollution, sponsored by Rutgers, The State University of New Jersey.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT05794087: Recruiting NA study of Air Pollution, sponsored by Rutgers, The State University of New Jersey.
NCT05794087 is a NA study of Air Pollution that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 120 participants, above the 45-participant average among 7 other Air Pollution trials with a reported enrollment target (167% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05794087, a NA study of Air Pollution, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to better understand the mechanisms of lung injury from ozone exposure. Subjects will participate in two exposure sessions: filtered air and 0.2 ppm ozone. The exposure visits will be at least 2 weeks apart. Subjects will be asked to produce sputum through coughing after each exposure. The samples will be analyzed for macrophage activity.
Primary Outcome
The metabolic activity of inflammatory cells in sputum will be assessed by the measurement of ATP production. The measurement will be made on an Agilent Seahorse using a Mitoplate Assay.
Conditions Studied
Interventions
- OTHER Clean Air
- OTHER Ozone
Study Locations (1)
New Jersey
- Rutgers - EOHSI - Piscataway
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2023-02-07 |
| Est. Completion | 2027-06-01 |
| Phase | NA |
What NCT05794087 shows while recruiting
NCT05794087 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, above the 45-participant average among 7 other Air Pollution trials with a reported enrollment target (167% higher).
The record links to 1 condition, with Air Pollution appearing as the primary indexed condition, and to 2 interventions - of which Clean Air is the first listed.
NCT05794087 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT05794087 about?
NCT05794087 is a clinical study titled "The Role of Macrophage Activation in Lung Injury Following Ozone Exposure". The purpose of the study is to better understand the mechanisms of lung injury from ozone exposure. Subjects will participate in two exposure sessions: filtered air and 0.2 ppm ozone. The exposure visits will be at least 2 weeks apart. Subjects will be asked to produce sputum through coughing after ...
What is the current status of trial NCT05794087?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2023-02-07. Estimated completion is 2027-06-01.
What conditions does trial NCT05794087 study?
This clinical trial studies the following conditions: Air Pollution.
What interventions are being tested in trial NCT05794087?
The interventions under investigation include: Clean Air (OTHER), Ozone (OTHER).
Who is sponsoring clinical trial NCT05794087?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05794087 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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