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NCT05792176 · ClinicalTrials.gov registry record · NA
Ukulele Playing to Improve Cognition in People with Multiple Sclerosis: a Feasibility Study
A NA study, sponsored by University of Texas at Austin.
- Completed
- Registry status
- NA
- Development phase
- 29
- Enrollment target
NCT05792176: Completed NA study, sponsored by University of Texas at Austin.
NCT05792176 is a NA study that has completed, run by University of Texas at Austin. The registered enrollment target is 29 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05792176, a NA study, has completed, sponsored by University of Texas at Austin.
- COMPLETED
- Registry status
- NA
- Development phase
- 29 participants
- Enrollment target
Study Summary
Over the past 10 years, the rates of multiple sclerosis (MS) have nearly doubled in the United States. This chronic, neuroinflammatory, and neurodegenerative disease is most often diagnosed between the ages of 20-40. Cognitive impairment effects up to 70% of people with MS (PwMS) and has a detrimental impact on mental health, social connections, and employment. Further, up to 50% of PwMS also struggle with depression. Numerous cognitive rehabilitation programs are available to address cognitive impairment, but few interventions have simultaneous effects on cognition and emotional well-being. Music interventions have potential to fill this gap. Brain imaging studies on music and emotion show that music can modulate activity in the brains structures that are known to be crucially involved in emotion. Further, music engages areas of the brain that are involved with paying attention, making predictions, and updating events in our memory. The purpose of this study is to determine the feasibility of an online musical training intervention (MTI) for PwMS and explore the potential effect on cognition, psychosocial, and functional well-being compared to an active control group (music listening (ML)). The specific aims are to: 1) determine the feasibility and acceptability of delivering the MTI virtually over three months to PwMS; 2) evaluate the effect of the MTI on cognitive functioning (processing speed, working memory, cognitive flexibility, response inhibition), psychosocial (anxiety, depression, stress, quality of life, self-efficacy) and functional (insomnia) well-being compared to ML; and 3) (exploratory aim) to utilize non-invasive neuroimaging to determine if pre-intervention brain activity predicts post-intervention cognitive functioning.
Primary Outcome
Feasibility will be evaluated by tracking the percentage of participants screened and enrolled.
Interventions
- BEHAVIORAL Music Listening
- BEHAVIORAL Music Training Intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2023-03-27 |
| Est. Completion | 2024-10-01 |
| Phase | NA |
What the finished NCT05792176 record still lists
NCT05792176 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Music Listening is the first listed.
NCT05792176 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05792176 about?
NCT05792176 is a clinical study titled "Ukulele Playing to Improve Cognition in People with Multiple Sclerosis: a Feasibility Study". Over the past 10 years, the rates of multiple sclerosis (MS) have nearly doubled in the United States. This chronic, neuroinflammatory, and neurodegenerative disease is most often diagnosed between the ages of 20-40. Cognitive impairment effects up to 70% of people with MS (PwMS) and has a detriment...
What is the current status of trial NCT05792176?
This trial is currently completed. It is a NA study. The enrollment target is 29 participants. The study started on 2023-03-27. Estimated completion is 2024-10-01.
What interventions are being tested in trial NCT05792176?
The interventions under investigation include: Music Listening (BEHAVIORAL), Music Training Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT05792176?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05792176's enrollment target sits among peer trials
29 1702nd of 2000 higher than 297 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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