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NCT05787470 · ClinicalTrials.gov registry record
State of Hormones Impact Nociceptive Expression
A clinical trial of Pain and Gender Identity, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- 120
- Enrollment target
- 1
- Study location
NCT05787470 is a study of Pain and Gender Identity that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 120 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (61% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05787470, a study of Pain and Gender Identity, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The Investigators have recently published on differences in pain sensitivity measures between cis and trans individuals in the local area. The investigators observed the anticipated differences in pain sensitivity between CM and CW (CW \> CM), but found that the TW were phenotypically similar to CW in all measures. However, the investigators did not assess hormone level, nor did the investigators recruit TM participants. Here, with the assistance of two local community group stakeholders the investigators will recruit the following groups: CM, CW, TM+T (currently taking exogenous testosterone), TW+E (exogenous estradiol), TM, and TW (n=20/group). The investigators will use quantitative sensory testing to assess sensitivity to cold, pressure, and heat via standardized protocols. Blood samples will be taken for assessment of stress and reproductive hormone levels, immune cell populations and stimulated cytokine release. Finally, questionnaires will measure pain state, quality of life (QOL), voice QOL, body image, appearance, self-reported health, masculinity/femininity, community connectedness, gender role, sleep, depression, social support, adverse childhood experiences and stigma.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Blood Draw
- BEHAVIORAL Quantative sensory testing
Study Locations (1)
Alabama
- University of Alabama at Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2023-03-01 |
| Est. Completion | 2026-07-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05787470
The ClinicalTrials.gov registry entry for NCT05787470 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 304-participant average among 374 other Pain trials with a reported enrollment target (61% lower). The listed sponsor is University of Alabama at Birmingham, which has 1,160 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Pain appearing as the primary indexed condition, and to 2 interventions - of which Blood Draw is the first listed.
NCT05787470 reports 1 study location spanning 1 distinct geographic area - top geographies include Alabama.
Frequently Asked Questions
What is clinical trial NCT05787470 about?
NCT05787470 is a clinical study titled "State of Hormones Impact Nociceptive Expression". The Investigators have recently published on differences in pain sensitivity measures between cis and trans individuals in the local area. The investigators observed the anticipated differences in pain sensitivity between CM and CW (CW \> CM), but found that the TW were phenotypically similar to CW ...
What is the current status of trial NCT05787470?
This trial is currently recruiting. The enrollment target is 120 participants. The study started on 2023-03-01. Estimated completion is 2026-07-31.
What conditions does trial NCT05787470 study?
This clinical trial studies the following conditions: Pain, Gender Identity.
What interventions are being tested in trial NCT05787470?
The interventions under investigation include: Blood Draw (DIAGNOSTIC_TEST), Quantative sensory testing (BEHAVIORAL).
Who is sponsoring clinical trial NCT05787470?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05787470 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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