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NCT05777187 · ClinicalTrials.gov registry record · NA
Mitigation of Postoperative Delirium in High-Risk Patients
A NA study, sponsored by Icahn School of Medicine at Mount Sinai.
- Terminated
- Registry status
- NA
- Development phase
- 7,412
- Enrollment target
NCT05777187: Clinical Trial NA study, sponsored by Icahn School of Medicine at Mount Sinai.
NCT05777187 is a NA study that was terminated before completion, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 7,412 participants, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (428% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05777187, a NA study, was terminated before completion, sponsored by Icahn School of Medicine at Mount Sinai.
- TERMINATED
- Registry status
- NA
- Development phase
- 7,412 participants
- Enrollment target
Study Summary
Among patients with cognitive impairment (CI) that undergo surgery, the risk for developing postoperative delirium (POD) is high (50%) and associated with further morbidity and mortality. Yet, 30-40% of POD cases are preventable with perioperative management. This randomized pragmatic clinical trial aims to assess incidence of POD in adult surgical patients with CI, as well as provider adherence to a set of 12 perioperative best practice recommendations for perioperative management. Electronic health record (EHR) data will be used to identify patients as high risk for developing POD and clinical decision support (CDS) prompts within the EHR will display best practices. Cases will be randomized to either the control group, usual care or the intervention which includes the high-risk alert and best practice prompts.
Primary Outcome
Postoperative Delirium measured using the 4 A's Test (4AT) delirium assessment documentation. The 4AT is a commonly used tool that identifies the presence/absence of Postoperative Delirium (POD). It consists of 4 sections; alertness, AMT4: Abbreviated Mental Test -4, attention, and acute change of fluctuating course. The 4AT is scored from 0-12, with higher score indicating poorer health outcomes. Scoring: 4 or above: possible delirium +/- cognitive impairment 1-3: possible cognitive impairme
Interventions
- OTHER Clinical Decision Support
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7,412 participants |
| Start Date | 2023-06-20 |
| Est. Completion | 2024-08-31 |
| Phase | NA |
Why NCT05777187 stopped before completion
NCT05777187 is an interventional study that assigns participants to a tested intervention. Its 7,412 participants enrollment target places it among the larger protocols in the corpus, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (428% higher).
The record links to 0 conditions, and to 1 intervention - of which Clinical Decision Support is the first listed.
NCT05777187 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05777187 about?
NCT05777187 is a clinical study titled "Mitigation of Postoperative Delirium in High-Risk Patients". Among patients with cognitive impairment (CI) that undergo surgery, the risk for developing postoperative delirium (POD) is high (50%) and associated with further morbidity and mortality. Yet, 30-40% of POD cases are preventable with perioperative management. This randomized pragmatic clinical trial...
What is the current status of trial NCT05777187?
This trial is currently terminated. It is a NA study. The enrollment target is 7,412 participants. The study started on 2023-06-20. Estimated completion is 2024-08-31.
What interventions are being tested in trial NCT05777187?
The interventions under investigation include: Clinical Decision Support (OTHER).
Who is sponsoring clinical trial NCT05777187?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05777187's enrollment target sits among peer trials
7,412 20th of 2000 higher than 1,981 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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