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NCT05768347 · ClinicalTrials.gov registry record · Phase 1

Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC

A Phase 1 study of Urothelial Carcinoma and Non-Invasive Bladder Urothelial Carcinoma, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Active
Registry status
Phase 1
Development phase
9
Enrollment target
1
Study location

NCT05768347 is a Phase 1 study of Urothelial Carcinoma and Non-Invasive Bladder Urothelial Carcinoma that is active but no longer recruiting, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 9 participants, below the 239-participant average among 85 other Urothelial Carcinoma trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05768347, a Phase 1 study of Urothelial Carcinoma and Non-Invasive Bladder Urothelial Carcinoma, is active but no longer recruiting, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
9 participants
Enrollment target
1
Study location

Study Summary

The purpose of the study is to evaluate the feasibility, safety and tolerability of intravesical adoptive cell therapy using TIL (tumor infiltrating lymphocytes) in participants with urothelial cell carcinoma (UCC) non-muscle invasive bladder cancer (NMIBC).

Interventions

  • BIOLOGICAL Adoptive Cell Therapy with Tumor-infiltrating Lymphocytes (TIL)

Study Locations (1)

Florida

  • Moffitt Cancer Center - Tampa

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2023-08-10
Est. Completion 2027-01
Phase Phase 1

What the Registry Record Tells You About NCT05768347

The ClinicalTrials.gov registry entry for NCT05768347 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 239-participant average among 85 other Urothelial Carcinoma trials with a reported enrollment target (96% lower). The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Urothelial Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which Adoptive Cell Therapy with Tumor-infiltrating Lymphocytes (TIL) is the first listed.

NCT05768347 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT05768347 about?

NCT05768347 is a clinical study titled "Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC". The purpose of the study is to evaluate the feasibility, safety and tolerability of intravesical adoptive cell therapy using TIL (tumor infiltrating lymphocytes) in participants with urothelial cell carcinoma (UCC) non-muscle invasive bladder cancer (NMIBC).

What is the current status of trial NCT05768347?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2023-08-10. Estimated completion is 2027-01.

What conditions does trial NCT05768347 study?

This clinical trial studies the following conditions: Urothelial Carcinoma, Non-Invasive Bladder Urothelial Carcinoma.

What interventions are being tested in trial NCT05768347?

The interventions under investigation include: Adoptive Cell Therapy with Tumor-infiltrating Lymphocytes (TIL) (BIOLOGICAL).

Who is sponsoring clinical trial NCT05768347?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05768347 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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