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NCT05758701 · ClinicalTrials.gov registry record · Phase 4

CT TAVR Abdomen Study

A Phase 4 study of Transcatheter Aortic Valve Replacement, sponsored by University of Maryland, Baltimore.

Recruiting
Registry status
Phase 4
Development phase
164
Enrollment target
1
Study location

NCT05758701 is a Phase 4 study of Transcatheter Aortic Valve Replacement that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 164 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT05758701, a Phase 4 study of Transcatheter Aortic Valve Replacement, is actively recruiting participants, sponsored by University of Maryland, Baltimore.

RECRUITING
Registry status
Phase 4
Development phase
164 participants
Enrollment target
1
Study location

Study Summary

A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search for alternative methods or doses. Reducing iodinated IV contrast dose can mitigate IV contrast supply shortages and enable significant cost savings for the radiology practice and hospital system. In addition, decreased IV contrast dose can potentially reduce the rate of acute kidney injury, specifically in patients with decreased renal function. The purpose of the study is to determine whether low IV contrast dose CT with monoenergetic reconstruction can be use for presurgical planning of transcatheter valve replacement (TAVR) procedure.

Interventions

  • COMBINATION_PRODUCT Iodinated Contrast Agent (Omnipaque)
  • DEVICE Dual Energy CT

Study Locations (1)

Maryland

  • University of Maryland Medical Center - Baltimore

Trial Details

FieldValue
Enrollment Target 164 participants
Start Date 2023-09-19
Est. Completion 2027-03-01
Phase Phase 4

Sponsor

University of Maryland, Baltimore

560 total trials

What the Registry Record Tells You About NCT05758701

The ClinicalTrials.gov registry entry for NCT05758701 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 164 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Transcatheter Aortic Valve Replacement appearing as the primary indexed condition, and to 2 interventions - of which Iodinated Contrast Agent (Omnipaque) is the first listed.

NCT05758701 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT05758701 about?

NCT05758701 is a clinical study titled "CT TAVR Abdomen Study". A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search for alternative methods or doses. Reducing iodinated IV contrast dose can mitigate IV contrast suppl...

What is the current status of trial NCT05758701?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 164 participants. The study started on 2023-09-19. Estimated completion is 2027-03-01.

What conditions does trial NCT05758701 study?

This clinical trial studies the following conditions: Transcatheter Aortic Valve Replacement.

What interventions are being tested in trial NCT05758701?

The interventions under investigation include: Iodinated Contrast Agent (Omnipaque) (COMBINATION_PRODUCT), Dual Energy CT (DEVICE).

Who is sponsoring clinical trial NCT05758701?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05758701 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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