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NCT05750498 · ClinicalTrials.gov registry record
A-LiNK: Improving Outcomes in Autoimmune Liver Disease
A clinical trial of Primary Sclerosing Cholangitis and Autoimmune Hepatitis, sponsored by Children's Hospital Medical Center, Cincinnati.
- Recruiting
- Registry status
- 800
- Enrollment target
- 8
- Study locations
NCT05750498 is a study of Primary Sclerosing Cholangitis and Autoimmune Hepatitis that is actively recruiting participants, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 800 participants, above the 518-participant average among 23 other Primary Sclerosing Cholangitis trials with a reported enrollment target (54% higher). The trial reports 8 study locations across 7 states.
The verdict
NCT05750498, a study of Primary Sclerosing Cholangitis and Autoimmune Hepatitis, is actively recruiting participants, sponsored by Children's Hospital Medical Center, Cincinnati.
- RECRUITING
- Registry status
- 800 participants
- Enrollment target
- 8
- Study locations
Study Summary
The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD). This study will establish a shared clinical registry and a learning health network for the participating sites focusing on collecting and transmitting clinical measurement data, information about processes, and participation in an improvement collaborative. Pediatric Autoimmune Hepatitis (AIH) and Primary Sclerosing Cholangitis (PSC), represent a spectrum of AILD which present unique diagnostic and therapeutic challenges.A lack of accepted guidelines for disease monitoring or symptom management results in wide treatment variation with liver transplants indicated in refractory, progressive disease. The aims of A-LiNK are to: 1.) Create a learning health network focused on patient-centered outcomes research characterized by transparent sharing among centers, common priorities, and feasible plans for implementing new practices; 2) shift from traditional investigator-driven study to a patient and family-centered approach, and 3.) improve clinical outcomes and quality of life for pediatric AILD patients.
Conditions Studied
Interventions
- OTHER No interventions
Study Locations (8)
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
- Nationwide Children's Hospital - Columbus
California
- Stanford University - Palo Alto
Indiana
- Riley Children's Health - Indianapolis
Missouri
- St. Louis Children's Hospital - St Louis
Pennsylvania
- UPMC Children's Hospital of Pittsburgh - Pittsburgh
Texas
- UT Southwestern Medical Center - Dallas
Washington
- Seattle Children's Hospital - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 800 participants |
| Start Date | 2022-04-28 |
| Est. Completion | 2033-06-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05750498
The ClinicalTrials.gov registry entry for NCT05750498 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 800 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 518-participant average among 23 other Primary Sclerosing Cholangitis trials with a reported enrollment target (54% higher). The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 571 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Primary Sclerosing Cholangitis appearing as the primary indexed condition, and to 1 intervention - of which No interventions is the first listed.
NCT05750498 reports 8 study locations spanning 7 distinct geographic areas - top geographies include Ohio, California, Indiana.
Frequently Asked Questions
What is clinical trial NCT05750498 about?
NCT05750498 is a clinical study titled "A-LiNK: Improving Outcomes in Autoimmune Liver Disease". The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD). This study will establish a shared clinical registry and a learning health network for the participating sites focu...
What is the current status of trial NCT05750498?
This trial is currently recruiting. The enrollment target is 800 participants. The study started on 2022-04-28. Estimated completion is 2033-06-30.
What conditions does trial NCT05750498 study?
This clinical trial studies the following conditions: Primary Sclerosing Cholangitis, Autoimmune Hepatitis.
What interventions are being tested in trial NCT05750498?
The interventions under investigation include: No interventions (OTHER).
Who is sponsoring clinical trial NCT05750498?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05750498 being conducted?
This trial has 8 study locations across California, Indiana, Missouri, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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