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NCT05702645 · ClinicalTrials.gov registry record
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
A clinical trial of Down Syndrome and Myeloid Leukemia Associated With Down Syndrome, sponsored by Children's Oncology Group.
- Recruiting
- Registry status
- 330
- Enrollment target
- 20
- Study locations
NCT05702645 is a study of Down Syndrome and Myeloid Leukemia Associated With Down Syndrome that is actively recruiting participants, run by Children's Oncology Group. The registered enrollment target is 330 participants, below the 2,466-participant average among 54 other Down Syndrome trials with a reported enrollment target (87% lower). The trial reports 20 study locations across 9 states.
The verdict
NCT05702645, a study of Down Syndrome and Myeloid Leukemia Associated With Down Syndrome, is actively recruiting participants, sponsored by Children's Oncology Group.
- RECRUITING
- Registry status
- 330 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study attempts to learn more about the health of persons with Down syndrome after treatment for acute leukemia. Children with Down syndrome are at increased risk for side effects during treatment for acute leukemia, but it is unclear of their risk for long-term effects of cancer treatment. By learning more about the factors that may contribute to chronic health conditions and long-term effects after treatment for leukemia in persons with Down syndrome, clinical practice guidelines for survivorship care can be developed to help improve their quality-of-life.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Survey Administration
- OTHER Questionnaire Administration
- OTHER Clinical Evaluation
- OTHER Neurocognitive Assessment
Study Locations (20)
California
- Valley Children's Hospital - Madera
- UCSF Benioff Children's Hospital Oakland - Oakland
- Kaiser Permanente-Oakland - Oakland
- University of California Davis Comprehensive Cancer Center - Sacramento
- Rady Children's Hospital - San Diego - San Diego
- UCSF Medical Center-Mission Bay - San Francisco
Florida
- Golisano Children's Hospital of Southwest Florida - Fort Myers
- Memorial Regional Hospital/Joe DiMaggio Children's Hospital - Hollywood
- Nemours Children's Clinic-Jacksonville - Jacksonville
- Nemours Children's Hospital - Orlando
- Nemours Children's Clinic - Pensacola - Pensacola
- Saint Joseph's Hospital/Children's Hospital-Tampa - Tampa
Georgia
- Children's Healthcare of Atlanta - Arthur M Blank Hospital - Atlanta
- Augusta University Medical Center - Augusta
Alabama
- Children's Hospital of Alabama - Birmingham
Arizona
- Phoenix Childrens Hospital - Phoenix
Connecticut
- Yale University - New Haven
Delaware
- Alfred I duPont Hospital for Children - Wilmington
Hawaii
- Kapiolani Medical Center for Women and Children - Honolulu
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 330 participants |
| Start Date | 2023-11-30 |
| Est. Completion | 2029-06-30 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05702645
The ClinicalTrials.gov registry entry for NCT05702645 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 330 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,466-participant average among 54 other Down Syndrome trials with a reported enrollment target (87% lower). The listed sponsor is Children's Oncology Group, which has 342 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Down Syndrome appearing as the primary indexed condition, and to 5 interventions - of which Biospecimen Collection is the first listed.
NCT05702645 reports 20 study locations spanning 9 distinct geographic areas - top geographies include California, Florida, Georgia.
Frequently Asked Questions
What is clinical trial NCT05702645 about?
NCT05702645 is a clinical study titled "A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia". This study attempts to learn more about the health of persons with Down syndrome after treatment for acute leukemia. Children with Down syndrome are at increased risk for side effects during treatment for acute leukemia, but it is unclear of their risk for long-term effects of cancer treatment. By l...
What is the current status of trial NCT05702645?
This trial is currently recruiting. The enrollment target is 330 participants. The study started on 2023-11-30. Estimated completion is 2029-06-30.
What conditions does trial NCT05702645 study?
This clinical trial studies the following conditions: Down Syndrome, Myeloid Leukemia Associated With Down Syndrome, B Acute Lymphoblastic Leukemia Associated With Down Syndrome.
What interventions are being tested in trial NCT05702645?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Survey Administration (OTHER), Questionnaire Administration (OTHER), Clinical Evaluation (OTHER), Neurocognitive Assessment (OTHER).
Who is sponsoring clinical trial NCT05702645?
This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05702645 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Connecticut, Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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