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NCT05691439 · ClinicalTrials.gov registry record · NA
Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain Function
A NA study of Depression in Adolescence, sponsored by University of Oregon.
- Recruiting
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT05691439: Recruiting NA study of Depression in Adolescence, sponsored by University of Oregon.
NCT05691439 is a NA study of Depression in Adolescence that is actively recruiting participants, run by University of Oregon. The registered enrollment target is 150 participants, roughly in line with the 151-participant average among 7 other Depression in Adolescence trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05691439, a NA study of Depression in Adolescence, is actively recruiting participants, sponsored by University of Oregon.
- RECRUITING
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
This research will use biobehavioral approaches to generate understanding about the linkages between sleep duration and timing, stressful life events, and depressive symptoms in adolescents, with a long-term aim of developing effective preventative interventions.
Primary Outcome
The Patient-Reported Outcomes Measurement Information System (PROMIS) scale for Depression (8-item short form) will be administered at baseline, after each 2-week interval of intensive monitoring, and at follow-up, in reference to the past 7 days. The measure uses 5-point Likert scales, with scores ranging from 8 to 40 and higher scores indicating higher depression and lower scores indicating better outcome. Raw scores are converted to standardized T-scores using conversion tables published on t
Conditions Studied
Interventions
- BEHAVIORAL Sleep extension and advance
- BEHAVIORAL Regular sleep duration and timing
Study Locations (1)
Oregon
- University of Oregon - Eugene
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2023-03-27 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT05691439 shows while recruiting
NCT05691439 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 151-participant average among 7 other Depression in Adolescence trials with a reported enrollment target.
The record links to 1 condition, with Depression in Adolescence appearing as the primary indexed condition, and to 2 interventions - of which Sleep extension and advance is the first listed.
NCT05691439 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT05691439 about?
NCT05691439 is a clinical study titled "Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain Function". This research will use biobehavioral approaches to generate understanding about the linkages between sleep duration and timing, stressful life events, and depressive symptoms in adolescents, with a long-term aim of developing effective preventative interventions.
What is the current status of trial NCT05691439?
This trial is currently recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2023-03-27. Estimated completion is 2026-12-31.
What conditions does trial NCT05691439 study?
This clinical trial studies the following conditions: Depression in Adolescence.
What interventions are being tested in trial NCT05691439?
The interventions under investigation include: Sleep extension and advance (BEHAVIORAL), Regular sleep duration and timing (BEHAVIORAL).
Who is sponsoring clinical trial NCT05691439?
This trial is sponsored by University of Oregon, which has 63 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05691439 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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