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NCT05617495 · ClinicalTrials.gov registry record · NA
Mindfulness-Based fMRI Neurofeedback for Depression
A NA study of Depression in Adolescence and Rumination, sponsored by Columbia University.
- Recruiting
- Registry status
- NA
- Development phase
- 90
- Enrollment target
- 2
- Study locations
NCT05617495 is a NA study of Depression in Adolescence and Rumination that is actively recruiting participants, run by Columbia University. The registered enrollment target is 90 participants, below the 160-participant average among 7 other Depression in Adolescence trials with a reported enrollment target (44% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT05617495, a NA study of Depression in Adolescence and Rumination, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- NA
- Development phase
- 90 participants
- Enrollment target
- 2
- Study locations
Study Summary
In the United States, adolescents experience alarmingly high rates of major depression, and gold-standard treatments are only effective for approximately half of patients. Rumination may be a promising treatment target, as it is well-characterized at the neural level and contributes to depression onset, maintenance, and recurrence as well as predicts treatment non-response. Accordingly, the proposed research will investigate whether an innovative mindfulness-based real-time functional magnetic resonance imaging (fMRI) neurofeedback intervention successfully elicits change in the brain circuit underlying rumination to improve clinical outcomes among depressed adolescents.
Conditions Studied
Interventions
- OTHER Mindfulness + fMRI Neurofeedback
Study Locations (2)
Massachusetts
- Northeastern University - Boston
New York
- Columbia University Irving Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2024-04-10 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05617495
The ClinicalTrials.gov registry entry for NCT05617495 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 160-participant average among 7 other Depression in Adolescence trials with a reported enrollment target (44% lower). The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Depression in Adolescence appearing as the primary indexed condition, and to 1 intervention - of which Mindfulness + fMRI Neurofeedback is the first listed.
NCT05617495 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Massachusetts, New York.
Frequently Asked Questions
What is clinical trial NCT05617495 about?
NCT05617495 is a clinical study titled "Mindfulness-Based fMRI Neurofeedback for Depression". In the United States, adolescents experience alarmingly high rates of major depression, and gold-standard treatments are only effective for approximately half of patients. Rumination may be a promising treatment target, as it is well-characterized at the neural level and contributes to depression on...
What is the current status of trial NCT05617495?
This trial is currently recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2024-04-10. Estimated completion is 2026-06-30.
What conditions does trial NCT05617495 study?
This clinical trial studies the following conditions: Depression in Adolescence, Rumination.
What interventions are being tested in trial NCT05617495?
The interventions under investigation include: Mindfulness + fMRI Neurofeedback (OTHER).
Who is sponsoring clinical trial NCT05617495?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05617495 being conducted?
This trial has 2 study locations across Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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