Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05690282 · ClinicalTrials.gov registry record · Phase 4
Comparing Perioperative Outcomes in Pain Control
A Phase 4 study of Postoperative Pain, sponsored by University of California, San Diego.
- Active
- Registry status
- Phase 4
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05690282: Active Phase 4 study of Postoperative Pain, sponsored by University of California, San Diego.
NCT05690282 is a Phase 4 study of Postoperative Pain that is active but no longer recruiting, run by University of California, San Diego. The registered enrollment target is 100 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05690282, a Phase 4 study of Postoperative Pain, is active but no longer recruiting, sponsored by University of California, San Diego.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This project consists of a randomized controlled study design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and found to have an orthopaedic injury requiring surgery. Patients who consent to study participation will be randomized to receive either the multimodal pain management protocol or standard oral hydrocodone-acetaminophen for post-operative pain management. Data on opioid usage, pain control, and functional status will be collected for each participant. After 3 years of data collection, investigators will analyze this data to provide further insight in determining appropriateness of pain regimens that reduce the overall opioid consumption. Given the widespread opioid epidemic, it is imperative to develop alternative means to appropriately manage pain in orthopaedic surgery patients.
Primary Outcome
Morphine equivalents used over 1 year
Conditions Studied
Interventions
- DRUG Multimodal Pain Management (Ibuprofen/Acetaminophen/GABAPentin/0.25%Bupivacaine)
Study Locations (1)
California
- University of California, San Diego - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2021-05-17 |
| Est. Completion | 2026-05-17 |
| Phase | Phase 4 |
What the registry record for NCT05690282 still lists
NCT05690282 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (57% lower).
The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 1 intervention - of which Multimodal Pain Management (Ibuprofen/Acetaminophen/GABAPentin/0.25%Bupivacaine) is the first listed.
NCT05690282 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05690282 about?
NCT05690282 is a clinical study titled "Comparing Perioperative Outcomes in Pain Control". This project consists of a randomized controlled study design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and found to have an orthopaedic injury requiring surgery. Patients who consent to study participation will be randomized to receive either the mult...
What is the current status of trial NCT05690282?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 100 participants. The study started on 2021-05-17. Estimated completion is 2026-05-17.
What conditions does trial NCT05690282 study?
This clinical trial studies the following conditions: Postoperative Pain.
What interventions are being tested in trial NCT05690282?
The interventions under investigation include: Multimodal Pain Management (Ibuprofen/Acetaminophen/GABAPentin/0.25%Bupivacaine) (DRUG).
Who is sponsoring clinical trial NCT05690282?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05690282 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05690282's enrollment target sits among peer trials
100 55th of 120 higher than 59 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
RECRUITING · Phase 4
-
QL Block in Laparoscopic Myomectomy
RECRUITING · Phase 4
-
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
RECRUITING · Phase 4
-
A Study Of Corticosteroid On Postoperative Pain After Ureteroscopy For Urinary Calculi
RECRUITING · Phase 4
-
Preoperative Acetazolamide
RECRUITING · Phase 4
-
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
RECRUITING · Phase 4
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01048281 · 100 participants
Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
- NCT01161199 · 100 participants
The Use of Leukapheresis to Support HIV Pathogenesis Studies
- NCT01327690 · 100 participants · Early Phase 1
Mental Health in Veterans and Families After Group Therapies
- NCT01730781 · 100 participants
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI