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NCT05675527 · ClinicalTrials.gov registry record · Phase 4
PRP for Glenohumeral Osteoarthritis
A Phase 4 study of Shoulder Osteoarthritis, sponsored by Hospital for Special Surgery, New York.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 135
- Enrollment target
- 1
- Study location
NCT05675527: Recruiting Phase 4 study of Shoulder Osteoarthritis, sponsored by Hospital for Special Surgery, New York.
NCT05675527 is a Phase 4 study of Shoulder Osteoarthritis that is actively recruiting participants, run by Hospital for Special Surgery, New York. The registered enrollment target is 135 participants, below the 190-participant average among 9 other Shoulder Osteoarthritis trials with a reported enrollment target (29% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05675527, a Phase 4 study of Shoulder Osteoarthritis, is actively recruiting participants, sponsored by Hospital for Special Surgery, New York.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 135 participants
- Enrollment target
- 1
- Study location
Study Summary
The glenohumeral joint is the third most common large joint to be affected by OA. Conservative treatments include physical activity, corticosteroid injections, and medications. PRP is an emerging treatment that has shown efficacy in different musculoskeletal conditions. The use of PRP for glenohumeral OA has been described sparingly in the literature but has shown efficacy in a couple studies and case reports. However, all of the previous studies investigating PRP for glenohumeral OA have focused on low-dose PRP preparations (\~3X), and none have compared PRP treatment to saline treatment. This study aims to compare outcomes following single injections of low-dose PRP, high-dose PRP, or saline in patients with glenohumeral osteoarthritis.
Primary Outcome
The ASES measures pain and function in activities of daily living related to the shoulder. On a 100-point scale, a higher score represents less pain/higher function.
Conditions Studied
Interventions
- OTHER Saline
- BIOLOGICAL Low-dose PRP
- BIOLOGICAL High-dose PRP
Study Locations (1)
New York
- Hospital for Special Surgery - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 135 participants |
| Start Date | 2023-05-02 |
| Est. Completion | 2026-09-01 |
| Phase | Phase 4 |
What NCT05675527 shows while recruiting
NCT05675527 is an interventional study that assigns participants to a tested intervention. The registered 135 participants enrollment target is mid-sized for trials with a published cap, below the 190-participant average among 9 other Shoulder Osteoarthritis trials with a reported enrollment target (29% lower).
The record links to 1 condition, with Shoulder Osteoarthritis appearing as the primary indexed condition, and to 3 interventions - of which Saline is the first listed.
NCT05675527 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05675527 about?
NCT05675527 is a clinical study titled "PRP for Glenohumeral Osteoarthritis". The glenohumeral joint is the third most common large joint to be affected by OA. Conservative treatments include physical activity, corticosteroid injections, and medications. PRP is an emerging treatment that has shown efficacy in different musculoskeletal conditions. The use of PRP for glenohumer...
What is the current status of trial NCT05675527?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 135 participants. The study started on 2023-05-02. Estimated completion is 2026-09-01.
What conditions does trial NCT05675527 study?
This clinical trial studies the following conditions: Shoulder Osteoarthritis.
What interventions are being tested in trial NCT05675527?
The interventions under investigation include: Saline (OTHER), Low-dose PRP (BIOLOGICAL), High-dose PRP (BIOLOGICAL).
Who is sponsoring clinical trial NCT05675527?
This trial is sponsored by Hospital for Special Surgery, New York, which has 194 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05675527 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Shoulder Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05675527's enrollment target sits among peer trials
135 4th of 9 higher than 6 of 9 other Shoulder Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Shoulder Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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