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NCT05653778 · ClinicalTrials.gov registry record · NA
Scrambler Therapy for Corticobasal Syndrome-Associated Pain
A NA study of Corticobasal Degeneration and Corticobasal Syndrome, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- NA
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT05653778: Recruiting NA study of Corticobasal Degeneration and Corticobasal Syndrome, sponsored by Johns Hopkins University.
NCT05653778 is a NA study of Corticobasal Degeneration and Corticobasal Syndrome that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 25 participants, below the 1,985-participant average among 7 other Corticobasal Degeneration trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05653778, a NA study of Corticobasal Degeneration and Corticobasal Syndrome, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this pilot trial is to test whether scrambler therapy (ST) is an effective treatment for neuropathic pain in patients with corticobasal syndrome (CBS). The main question it aims to answer is: Will ST reduce pain scores by at least 33% at one month in this pilot trial, justifying further multi-center trials? Participants will: * be randomly assigned treatment from either transcutaneous electrical nerve stimulation (TENS) or ST for pain initially (eventually all patients will receive ST). * have superficial electrocardiogram (ECG) electrodes placed on the dermatomes involved with pain * obtain treatment lasting 30-40 minutes or until pain relief is obtained Researchers will compare patient's response to pain relief with TENS and ST to determine if ST is an effective treatment for central neuropathic pain.
Primary Outcome
The primary objective is to determine the change in patient-reported average daily pain from Day 0 to Day 30 and 90 as measured on a numerical scale of 0-10 (0=no pain; 10=worst pain in life) using the Modified Brief Pain Index.
Conditions Studied
Interventions
- DEVICE Scrambler therapy
- DEVICE TENS treatment
Study Locations (1)
Maryland
- Johns Hopkins School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2024-04-05 |
| Est. Completion | 2027-02 |
| Phase | NA |
What NCT05653778 shows while recruiting
NCT05653778 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 1,985-participant average among 7 other Corticobasal Degeneration trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Corticobasal Degeneration appearing as the primary indexed condition, and to 2 interventions - of which Scrambler therapy is the first listed.
NCT05653778 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05653778 about?
NCT05653778 is a clinical study titled "Scrambler Therapy for Corticobasal Syndrome-Associated Pain". The goal of this pilot trial is to test whether scrambler therapy (ST) is an effective treatment for neuropathic pain in patients with corticobasal syndrome (CBS). The main question it aims to answer is: Will ST reduce pain scores by at least 33% at one month in this pilot trial, justifying furthe...
What is the current status of trial NCT05653778?
This trial is currently recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2024-04-05. Estimated completion is 2027-02.
What conditions does trial NCT05653778 study?
This clinical trial studies the following conditions: Corticobasal Degeneration, Corticobasal Syndrome, Pain, Neuropathic.
What interventions are being tested in trial NCT05653778?
The interventions under investigation include: Scrambler therapy (DEVICE), TENS treatment (DEVICE).
Who is sponsoring clinical trial NCT05653778?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05653778 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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