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ACTIVE NOT RECRUITING

Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF

NCT05639556 · View on ClinicalTrials.gov ↗

Study Summary

The goal of the study is to examine multiple markers of anthropometrics, body composition, sarcopenia and frailty and compare them to dual energy X-ray absorptiometry (DXA) output, which is considered the current clinical gold-standard tool to measure body composition. The result of this study will provide detailed data regarding the nutrition and body composition within this Cystic Fibrosis population and also provide a baseline evaluation for use of these biomarkers in the future studies including evaluation of nutritional intervention. Further, the study will also include psychosocial and other patient-reported outcomes and medical contributors to understand their contributions to the nutritional failure in the adult advanced lung disease population. Finally, the study will evaluate both established and emerging nutritional and body composition parameters and link them to clinical outcomes in adults with CF across the spectrum of pulmonary function.

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST BMI and lean mass index from DXA
  • DIAGNOSTIC_TEST Anthropometric Measurements
  • DIAGNOSTIC_TEST Hand-grip strength
  • DIAGNOSTIC_TEST Six-minute walk Test
  • DIAGNOSTIC_TEST Sit-to-Stand Test

Study Locations (20)

Massachusetts

  • Massachusetts General Hospital (MGH) — Boston
  • Boston Children's Hospital and Brigham and Women's CF Center — Boston

New York

  • New York Medical College (NYMC) — Hawthorne
  • Northwell LIJ Adult Cystic Fibrosis Center — New Hyde Park

Ohio

  • University of Cincinnati — Cincinnati
  • University Hospitals — Cleveland

Arizona

  • University of Arizona — Tucson

Arkansas

  • University of Arkansas for Medical Sciences (UAMS) — Little Rock

Georgia

  • Emory — Atlanta

Illinois

  • Northwestern University — Chicago

Iowa

  • University of Iowa — Iowa City

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2023-04-20
Est. Completion 2028-12

Sponsor

Jaeb Center for Health Research

134 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05639556

The ClinicalTrials.gov registry entry for NCT05639556 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jaeb Center for Health Research, which has 134 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Cystic Fibrosis appearing as the primary indexed condition, and to 5 interventions — of which BMI and lean mass index from DXA is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05639556 reports 20 study locations spanning 17 distinct geographic areas — top geographies include Massachusetts, New York, Ohio. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05639556 about?

NCT05639556 is a clinical study titled "Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF". The goal of the study is to examine multiple markers of anthropometrics, body composition, sarcopenia and frailty and compare them to dual energy X-ray absorptiometry (DXA) output, which is considered the current clinical gold-standard tool to measure body composition. The result of this study will ...

What is the current status of trial NCT05639556?

This trial is currently active not recruiting. The enrollment target is 300 participants. The study started on 2023-04-20. Estimated completion is 2028-12.

What conditions does trial NCT05639556 study?

This clinical trial studies the following conditions: Cystic Fibrosis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05639556?

The interventions under investigation include: BMI and lean mass index from DXA (DIAGNOSTIC_TEST), Anthropometric Measurements (DIAGNOSTIC_TEST), Hand-grip strength (DIAGNOSTIC_TEST), Six-minute walk Test (DIAGNOSTIC_TEST), Sit-to-Stand Test (DIAGNOSTIC_TEST). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05639556?

This trial is sponsored by Jaeb Center for Health Research, which has 134 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05639556 being conducted?

This trial has 20 study locations across Arizona, Arkansas, Georgia, Illinois, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial