Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05639556 · ClinicalTrials.gov registry record
Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF
A clinical trial of Cystic Fibrosis, sponsored by Jaeb Center for Health Research.
- Active
- Registry status
- 300
- Enrollment target
- 20
- Study locations
NCT05639556: Active study of Cystic Fibrosis, sponsored by Jaeb Center for Health Research.
NCT05639556 is a study of Cystic Fibrosis that is active but no longer recruiting, run by Jaeb Center for Health Research. The registered enrollment target is 300 participants, above the 177-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (69% higher). The trial reports 20 study locations across 17 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05639556, a study of Cystic Fibrosis, is active but no longer recruiting, sponsored by Jaeb Center for Health Research.
- ACTIVE NOT RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 20
- Study locations
Study Summary
The goal of the study is to examine multiple markers of anthropometrics, body composition, sarcopenia and frailty and compare them to dual energy X-ray absorptiometry (DXA) output, which is considered the current clinical gold-standard tool to measure body composition. The result of this study will provide detailed data regarding the nutrition and body composition within this Cystic Fibrosis population and also provide a baseline evaluation for use of these biomarkers in the future studies including evaluation of nutritional intervention. Further, the study will also include psychosocial and other patient-reported outcomes and medical contributors to understand their contributions to the nutritional failure in the adult advanced lung disease population. Finally, the study will evaluate both established and emerging nutritional and body composition parameters and link them to clinical outcomes in adults with CF across the spectrum of pulmonary function.
Primary Outcome
Estimate and compare correlation between lean mass index from DXA (kg/m2) and BMI (kg/m2)
Conditions Studied
Interventions
- DIAGNOSTIC_TEST BMI and lean mass index from DXA
- DIAGNOSTIC_TEST Anthropometric Measurements
- DIAGNOSTIC_TEST Hand-grip strength
- DIAGNOSTIC_TEST Six-minute walk Test
- DIAGNOSTIC_TEST Sit-to-Stand Test
Study Locations (20)
Massachusetts
- Massachusetts General Hospital (MGH) - Boston
- Boston Children's Hospital and Brigham and Women's CF Center - Boston
New York
- New York Medical College (NYMC) - Hawthorne
- Northwell LIJ Adult Cystic Fibrosis Center - New Hyde Park
Ohio
- University of Cincinnati - Cincinnati
- University Hospitals - Cleveland
Arizona
- University of Arizona - Tucson
Arkansas
- University of Arkansas for Medical Sciences (UAMS) - Little Rock
Georgia
- Emory - Atlanta
Illinois
- Northwestern University - Chicago
Iowa
- University of Iowa - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2023-04-20 |
| Est. Completion | 2028-12 |
What the registry record for NCT05639556 still lists
NCT05639556 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 177-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (69% higher).
The record links to 1 condition, with Cystic Fibrosis appearing as the primary indexed condition, and to 5 interventions - of which BMI and lean mass index from DXA is the first listed.
NCT05639556 names 20 study sites across 17 states, led by Massachusetts, New York, Ohio.
Frequently Asked Questions
What is clinical trial NCT05639556 about?
NCT05639556 is a clinical study titled "Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF". The goal of the study is to examine multiple markers of anthropometrics, body composition, sarcopenia and frailty and compare them to dual energy X-ray absorptiometry (DXA) output, which is considered the current clinical gold-standard tool to measure body composition. The result of this study will ...
What is the current status of trial NCT05639556?
This trial is currently active not recruiting. The enrollment target is 300 participants. The study started on 2023-04-20. Estimated completion is 2028-12.
What conditions does trial NCT05639556 study?
This clinical trial studies the following conditions: Cystic Fibrosis.
What interventions are being tested in trial NCT05639556?
The interventions under investigation include: BMI and lean mass index from DXA (DIAGNOSTIC_TEST), Anthropometric Measurements (DIAGNOSTIC_TEST), Hand-grip strength (DIAGNOSTIC_TEST), Six-minute walk Test (DIAGNOSTIC_TEST), Sit-to-Stand Test (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05639556?
This trial is sponsored by Jaeb Center for Health Research, which has 119 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05639556 being conducted?
This trial has 20 study locations across Arizona, Arkansas, Georgia, Illinois, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cystic Fibrosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05639556's enrollment target sits among peer trials
300 22nd of 169 higher than 148 of 169 other Cystic Fibrosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cystic Fibrosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Exercise in Child Health
RECRUITING · NA
-
Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.
RECRUITING · Phase 2
-
A Pilot and Feasibility Study to Evaluate High vs Low Glycemic Index Mixed Meal Tolerance Test in Adolescents and Young Adults With Cystic Fibrosis
RECRUITING · NA
-
A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators
RECRUITING
-
Assessing Tenapanor as a Treatment of CF-related Constipation.
RECRUITING · Phase 3
-
Genetics of Insulin and Incretins in Cystic Fibrosis
RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00353483 · 300 participants
Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells
- NCT00588185 · 300 participants · NA
[18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer
- NCT00682032 · 300 participants · NA
The Effect of Beta-glucan in Non-Small Cell Lung Cancer
- NCT00870064 · 300 participants · NA
The Treatment of Type I Open Fractures in Pediatrics
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI