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NCT05608629 · ClinicalTrials.gov registry record · NA
Vagus Nerve Stimulation as Treatment for Long Covid
A NA study, sponsored by Icahn School of Medicine at Mount Sinai.
- Completed
- Registry status
- NA
- Development phase
- 17
- Enrollment target
NCT05608629: Completed NA study, sponsored by Icahn School of Medicine at Mount Sinai.
NCT05608629 is a NA study that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 17 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05608629, a NA study, has completed, sponsored by Icahn School of Medicine at Mount Sinai.
- COMPLETED
- Registry status
- NA
- Development phase
- 17 participants
- Enrollment target
Study Summary
Many patients do not recover following Covid infection. The resulting illness is called Long Covid. Because there is no agreed upon treatment for this ailment, the research team has decided to do an open label pilot study using non-invasive, transcutaneous stimulation of the auricular branch of the vagus nerve. Inclusion criteria required the patient to fulfill criteria for having chronic fatigue syndrome. To date, fourteen patients provided evaluable data. Eight of these fulfilled the study's requirements for treatment success.
Primary Outcome
Treatment success is defined as patient had to improve on 2 of the following: a 14% improvement in SF-36 -- physical function (0-100 scale, higher score = less disability; report of marked or moderate improvement (2-3 on a scale going from +3 to -3\] based on the treatment \[patient global indication of change (0-7, higher score = more improvement); going from fatigue case to no fatigue on Chalder fatigue scale (0-3, higher score = more fatigue; improvement on VAS of at least 2 points \[VAS
Interventions
- DEVICE Transcutaneous Non-Invasive Vagus Nerve Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2022-06-06 |
| Est. Completion | 2022-12-05 |
| Phase | NA |
What the finished NCT05608629 record still lists
NCT05608629 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Transcutaneous Non-Invasive Vagus Nerve Stimulation is the first listed.
NCT05608629 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05608629 about?
NCT05608629 is a clinical study titled "Vagus Nerve Stimulation as Treatment for Long Covid". Many patients do not recover following Covid infection. The resulting illness is called Long Covid. Because there is no agreed upon treatment for this ailment, the research team has decided to do an open label pilot study using non-invasive, transcutaneous stimulation of the auricular branch of the ...
What is the current status of trial NCT05608629?
This trial is currently completed. It is a NA study. The enrollment target is 17 participants. The study started on 2022-06-06. Estimated completion is 2022-12-05.
What interventions are being tested in trial NCT05608629?
The interventions under investigation include: Transcutaneous Non-Invasive Vagus Nerve Stimulation (DEVICE).
Who is sponsoring clinical trial NCT05608629?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05608629's enrollment target sits among peer trials
17 1871st of 2000 higher than 130 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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