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NCT05600764 · ClinicalTrials.gov registry record
The Natural History of TRPV4 Neuropathy
A clinical trial of TRPV4 Gene Mutation, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- 70
- Enrollment target
- 1
- Study location
NCT05600764: Recruiting study of TRPV4 Gene Mutation, sponsored by Johns Hopkins University.
NCT05600764 is a study of TRPV4 Gene Mutation that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 70 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05600764, a study of TRPV4 Gene Mutation, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this research is to document the natural history of neuropathy in patients with a confirmed genetic mutation in the TRPV4 gene. The investigators are searching for patients willing to participate in a 6-year long study to document the symptoms of TRPV4-associated disease and their progression over time. Participation requires annual study visits at Johns Hopkins for adult and juvenile participants.
Primary Outcome
The Charcot Marie Tooth neuropathy score (CMTNS) which is an overall score that incorporates the sub-scores of Charcot Marie Tooth exam score (CMTES) and the Charcot Marie Tooth symptom score (CMTSS) which are all assessed at once. The minimum score is 0, the maximum score is 20, and higher scores indicate more severe disease.
Conditions Studied
Study Locations (1)
Maryland
- Johns Hopkins - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2023-12-15 |
| Est. Completion | 2048-12 |
What NCT05600764 shows while recruiting
NCT05600764 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 70 participants, a relatively small participant target.
The record links to 1 condition, with TRPV4 Gene Mutation appearing as the primary indexed condition, and to 0 interventions.
NCT05600764 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05600764 about?
NCT05600764 is a clinical study titled "The Natural History of TRPV4 Neuropathy". The goal of this research is to document the natural history of neuropathy in patients with a confirmed genetic mutation in the TRPV4 gene. The investigators are searching for patients willing to participate in a 6-year long study to document the symptoms of TRPV4-associated disease and their progre...
What is the current status of trial NCT05600764?
This trial is currently recruiting. The enrollment target is 70 participants. The study started on 2023-12-15. Estimated completion is 2048-12.
What conditions does trial NCT05600764 study?
This clinical trial studies the following conditions: TRPV4 Gene Mutation.
Who is sponsoring clinical trial NCT05600764?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05600764 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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