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NCT05576922 · ClinicalTrials.gov registry record · NA

Collagen Matrix + rhPDGF-BB vs Connective Tissue Graft for the Treatment of Peri-implant Soft Tissue Dehiscences

A NA study of Implant Complication, sponsored by Harvard Medical School (HMS and HSDM).

Active
Registry status
NA
Development phase
28
Enrollment target
1
Study location

NCT05576922: Active NA study of Implant Complication, sponsored by Harvard Medical School (HMS and HSDM).

NCT05576922 is a NA study of Implant Complication that is active but no longer recruiting, run by Harvard Medical School (HMS and HSDM). The registered enrollment target is 28 participants, below the 90-participant average among 3 other Implant Complication trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05576922, a NA study of Implant Complication, is active but no longer recruiting, sponsored by Harvard Medical School (HMS and HSDM).

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
28 participants
Enrollment target
1
Study location

Study Summary

The study aims at comparing two different approaches for the treatment of implant esthetic complications (peri-implant soft tissue dehiscences): autogenous connective tissue graft vs collagen matrix + recombinant human platelet derived growth factor-BB

Primary Outcome

Reduction of the depth of the Soft tissue dehiscence (vertical measurement of the complication, in relation to the level of the cemento-enamel junction of the contralateral homologous tooth) compared to baseline (expressed in millimeters)

Conditions Studied

Interventions

  • OTHER Prosthetic-surgical approach + autogenous graft
  • OTHER Prosthetic-surgical approach + graft substitute

Study Locations (1)

Massachusetts

  • Harvard School of Dental Medicine - Boston

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2023-01-04
Est. Completion 2025-10-21
Phase NA

What the registry record for NCT05576922 still lists

NCT05576922 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 90-participant average among 3 other Implant Complication trials with a reported enrollment target (69% lower).

The record links to 1 condition, with Implant Complication appearing as the primary indexed condition, and to 2 interventions - of which Prosthetic-surgical approach + autogenous graft is the first listed.

NCT05576922 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05576922 about?

NCT05576922 is a clinical study titled "Collagen Matrix + rhPDGF-BB vs Connective Tissue Graft for the Treatment of Peri-implant Soft Tissue Dehiscences". The study aims at comparing two different approaches for the treatment of implant esthetic complications (peri-implant soft tissue dehiscences): autogenous connective tissue graft vs collagen matrix + recombinant human platelet derived growth factor-BB

What is the current status of trial NCT05576922?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 28 participants. The study started on 2023-01-04. Estimated completion is 2025-10-21.

What conditions does trial NCT05576922 study?

This clinical trial studies the following conditions: Implant Complication.

What interventions are being tested in trial NCT05576922?

The interventions under investigation include: Prosthetic-surgical approach + autogenous graft (OTHER), Prosthetic-surgical approach + graft substitute (OTHER).

Who is sponsoring clinical trial NCT05576922?

This trial is sponsored by Harvard Medical School (HMS and HSDM), which has 26 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05576922 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Source: ClinicalTrials.gov NCT05576922, the US trial registry maintained by the National Library of Medicine. NCT05576922 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.