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NCT05563610 · ClinicalTrials.gov registry record · Phase 4

Oral Penicillin Challenge and Allergy De-labeling in Children

A Phase 4 study, sponsored by Phoenix Children's Hospital.

Terminated
Registry status
Phase 4
Development phase
31
Enrollment target

NCT05563610: Clinical Trial Phase 4 study, sponsored by Phoenix Children's Hospital.

NCT05563610 is a Phase 4 study that was terminated before completion, run by Phoenix Children's Hospital. The registered enrollment target is 31 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05563610, a Phase 4 study, was terminated before completion, sponsored by Phoenix Children's Hospital.

TERMINATED
Registry status
Phase 4
Development phase
31 participants
Enrollment target

Study Summary

The primary purpose of this study is to investigate the portion of penicillin allergy labels that are not true allergies using oral amoxicillin challenges among pediatric patients. The secondary purpose is to evaluate the safety and feasibility of administering oral penicillin allergy challenges in the Pediatric Emergency Department.

Primary Outcome

Percentage of study patients presenting to the pediatric ED who received the amoxicillin oral challenge who demonstrated a true IgE-mediated allergic reaction

Interventions

  • DRUG Amoxicillin 500mg

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2022-09-26
Est. Completion 2024-06-12
Phase Phase 4
Phoenix Children's Hospital

26 total trials

Why NCT05563610 stopped before completion

NCT05563610 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 1 intervention - of which Amoxicillin 500mg is the first listed.

NCT05563610 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05563610 about?

NCT05563610 is a clinical study titled "Oral Penicillin Challenge and Allergy De-labeling in Children". The primary purpose of this study is to investigate the portion of penicillin allergy labels that are not true allergies using oral amoxicillin challenges among pediatric patients. The secondary purpose is to evaluate the safety and feasibility of administering oral penicillin allergy challenges in ...

What is the current status of trial NCT05563610?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 31 participants. The study started on 2022-09-26. Estimated completion is 2024-06-12.

What interventions are being tested in trial NCT05563610?

The interventions under investigation include: Amoxicillin 500mg (DRUG).

Who is sponsoring clinical trial NCT05563610?

This trial is sponsored by Phoenix Children's Hospital, which has 26 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05563610's enrollment target sits among peer trials

31 1544th of 2000 higher than 449 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05563610, the US trial registry maintained by the National Library of Medicine. NCT05563610 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.