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NCT05546697 · ClinicalTrials.gov registry record · NA
Comparing Behavior Therapy and Yoga for Treating Depression Among Adults
A NA study of Depression, sponsored by Massachusetts General Hospital.
- Active
- Registry status
- NA
- Development phase
- 518
- Enrollment target
- 1
- Study location
NCT05546697: Active NA study of Depression, sponsored by Massachusetts General Hospital.
NCT05546697 is a NA study of Depression that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 518 participants, below the 785-participant average among 679 other Depression trials with a reported enrollment target (34% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05546697, a NA study of Depression, is active but no longer recruiting, sponsored by Massachusetts General Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 518 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a parallel group study design. The investigators propose to compare an online, synchronous group-based yoga intervention developed for individuals with depression to an online, synchronous individualized, evidence-based behavioral therapy for depression, or Brief Behavioral Activation Treatment for Depression (BA). This study is a multi-site randomized trial of adults with clinically significant depressive symptoms. Participants (N=518) will be randomized in an equal allocation ratio (i.e., 1:1) across two intervention groups: yoga and BA. Interventions will be provided over a 12-week period and assessments will occur at baseline (week 0), week 6, week 12, week 18, and week 24.
Primary Outcome
It is a 9-item self-report questionnaire that is widely used to assess depression symptom severity. A PHQ-9 score ≥10 has a sensitivity of 88% and a specificity of 88% for major depression. PHQ-9 scores of 5, 10, 15, and 20 represented mild, moderate, moderately severe, and severe depression, respectively.
Conditions Studied
Interventions
- OTHER Online- Yoga-based Intervetion
- BEHAVIORAL Online- BA
Study Locations (1)
Massachusetts
- Giuliana Chau - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 518 participants |
| Start Date | 2023-02-13 |
| Est. Completion | 2026-05-01 |
| Phase | NA |
What the registry record for NCT05546697 still lists
NCT05546697 is an interventional study that assigns participants to a tested intervention. The registered 518 participants enrollment target is mid-sized for trials with a published cap, below the 785-participant average among 679 other Depression trials with a reported enrollment target (34% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Online- Yoga-based Intervetion is the first listed.
NCT05546697 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05546697 about?
NCT05546697 is a clinical study titled "Comparing Behavior Therapy and Yoga for Treating Depression Among Adults". This is a parallel group study design. The investigators propose to compare an online, synchronous group-based yoga intervention developed for individuals with depression to an online, synchronous individualized, evidence-based behavioral therapy for depression, or Brief Behavioral Activation Treatm...
What is the current status of trial NCT05546697?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 518 participants. The study started on 2023-02-13. Estimated completion is 2026-05-01.
What conditions does trial NCT05546697 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT05546697?
The interventions under investigation include: Online- Yoga-based Intervetion (OTHER), Online- BA (BEHAVIORAL).
Who is sponsoring clinical trial NCT05546697?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05546697 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05546697's enrollment target sits among peer trials
518 77th of 679 higher than 603 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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