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NCT05538533 · ClinicalTrials.gov registry record · NA
Hypofractionated Preoperative Radiation for Head and Neck Cancers (HyPR-HN)
A NA study of Head and Neck Cancer, sponsored by Medical College of Wisconsin.
- Active
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT05538533: Active NA study of Head and Neck Cancer, sponsored by Medical College of Wisconsin.
NCT05538533 is a NA study of Head and Neck Cancer that is active but no longer recruiting, run by Medical College of Wisconsin. The registered enrollment target is 12 participants, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05538533, a NA study of Head and Neck Cancer, is active but no longer recruiting, sponsored by Medical College of Wisconsin.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a phase 1 study to determine the safety of a condensed preoperative radiation regimen (10, 7, or 5 fractions) for the management of head and neck squamous cell carcinoma.
Primary Outcome
Inoperability after HyPR-HN, is defined as an inability to proceed to surgery within eight weeks of radiation.
Conditions Studied
Interventions
- RADIATION 46 Gy Radiation Therapy
- RADIATION 40 Gy Radiation Therapy
- RADIATION 35 Gy Radiation Therapy
Study Locations (1)
Wisconsin
- Froedtert Hospital and the Medical College of Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2023-01-06 |
| Est. Completion | 2026-08 |
| Phase | NA |
What the registry record for NCT05538533 still lists
NCT05538533 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Head and Neck Cancer appearing as the primary indexed condition, and to 3 interventions - of which 46 Gy Radiation Therapy is the first listed.
NCT05538533 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT05538533 about?
NCT05538533 is a clinical study titled "Hypofractionated Preoperative Radiation for Head and Neck Cancers (HyPR-HN)". This is a phase 1 study to determine the safety of a condensed preoperative radiation regimen (10, 7, or 5 fractions) for the management of head and neck squamous cell carcinoma.
What is the current status of trial NCT05538533?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2023-01-06. Estimated completion is 2026-08.
What conditions does trial NCT05538533 study?
This clinical trial studies the following conditions: Head and Neck Cancer.
What interventions are being tested in trial NCT05538533?
The interventions under investigation include: 46 Gy Radiation Therapy (RADIATION), 40 Gy Radiation Therapy (RADIATION), 35 Gy Radiation Therapy (RADIATION).
Who is sponsoring clinical trial NCT05538533?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05538533 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Head and Neck Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05538533's enrollment target sits among peer trials
12 232nd of 250 higher than 15 of 250 other Head and Neck Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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