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A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults
NCT05526911 · View on ClinicalTrials.gov ↗
Study Summary
A Phase 1, Drug-Drug Interaction Study to Evaluate the Safety, Tolerability, and the Induction Potential of TBAJ-876 on CYP3A4 and P-glycoprotein and the Inhibition Potential of TBAJ-876 on P-glycoprotein in Healthy Adult Subjects
Conditions Studied
Interventions
- DRUG Midazolam
- DRUG Digoxin
- DRUG TBAJ-876
Study Locations (1)
New Jersey
- TKL Research, Inc. — Fair Lawn
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2022-06-30 |
| Est. Completion | 2022-09-26 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05526911
The ClinicalTrials.gov registry entry for NCT05526911 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Global Alliance for TB Drug Development, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 7 conditions, with Tuberculosis appearing as the primary indexed condition, and to 3 interventions — of which Midazolam is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05526911 reports 1 study location spanning 1 distinct geographic area — top geographies include New Jersey. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05526911 about?
NCT05526911 is a clinical study titled "A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults". A Phase 1, Drug-Drug Interaction Study to Evaluate the Safety, Tolerability, and the Induction Potential of TBAJ-876 on CYP3A4 and P-glycoprotein and the Inhibition Potential of TBAJ-876 on P-glycoprotein in Healthy Adult Subjects
What is the current status of trial NCT05526911?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2022-06-30. Estimated completion is 2022-09-26.
What conditions does trial NCT05526911 study?
This clinical trial studies the following conditions: Tuberculosis, Pulmonary Disease, Tuberculosis, Pulmonary, Multi Drug Resistant Tuberculosis, Drug Sensitive Tuberculosis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05526911?
The interventions under investigation include: Midazolam (DRUG), Digoxin (DRUG), TBAJ-876 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05526911?
This trial is sponsored by Global Alliance for TB Drug Development, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05526911 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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