Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05525923 · ClinicalTrials.gov registry record
Personalized Postoperative Pain Management Following Thoracic Surgery in Adults
A clinical trial of Thoracic Surgery and Lobectomy, sponsored by OpalGenix.
- Recruiting
- Registry status
- 200
- Enrollment target
- 4
- Study locations
NCT05525923 is a study of Thoracic Surgery and Lobectomy that is actively recruiting participants, run by OpalGenix. The registered enrollment target is 200 participants, above the 139-participant average among 5 other Thoracic Surgery trials with a reported enrollment target (44% higher). The trial reports 4 study locations across 1 state.
The verdict
NCT05525923, a study of Thoracic Surgery and Lobectomy, is actively recruiting participants, sponsored by OpalGenix.
- RECRUITING
- Registry status
- 200 participants
- Enrollment target
- 4
- Study locations
Study Summary
The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone, in adults following thoracic surgery. Major inpatient thoracic surgeries (TS) for lung disease are common and extremely painful surgeries and are associated with sever post-surgical pain, high incidence of chronic post-surgical pain (CPSP), excess opioid use, costly immediate postoperative opioid adverse events (AEs), and long hospital stays. This study is aiming to develop proactive risk prediction algorithms for precision surgical pain relief in adult TS patients through comparison of actual clinical outcomes with standard of care to predicted outcomes based on personalized risk assessments.
Conditions Studied
Study Locations (4)
Pennsylvania
- UPMC Presbyterian Hospital - Pittsburgh
- UPMC Mercy Hospital - Pittsburgh
- UPMC Shadyside Hospital - Pittsburgh
- UPMC Passavant Hospital - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2023-11-30 |
| Est. Completion | 2028-03-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05525923
The ClinicalTrials.gov registry entry for NCT05525923 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 139-participant average among 5 other Thoracic Surgery trials with a reported enrollment target (44% higher). The listed sponsor is OpalGenix, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Thoracic Surgery appearing as the primary indexed condition, and to 0 interventions.
NCT05525923 reports 4 study locations spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05525923 about?
NCT05525923 is a clinical study titled "Personalized Postoperative Pain Management Following Thoracic Surgery in Adults". The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone, in adults following thoracic surgery. Major inp...
What is the current status of trial NCT05525923?
This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2023-11-30. Estimated completion is 2028-03-01.
What conditions does trial NCT05525923 study?
This clinical trial studies the following conditions: Thoracic Surgery, Lobectomy, Segmentectomy, Pneumonectomy.
Who is sponsoring clinical trial NCT05525923?
This trial is sponsored by OpalGenix, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05525923 being conducted?
This trial has 4 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Thoracic Surgery
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial
RECRUITING · Phase 1
-
Amiodarone and N-Acetylcysteine or Amiodarone Alone for Preventing Atrial Fibrillation After Thoracic Surgery
ACTIVE NOT RECRUITING · Phase 3
-
Single Site Thoracic Surgery for Pediatric Pneumothorax
COMPLETED
-
Cerebral Autoregulation Monitoring During Cardiac Surgery
COMPLETED · NA
-
Biventricular Pacing In Patients With Left Ventricular Dysfunction After Cardiovascular Surgery
COMPLETED · Phase 3
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.