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NCT05525923 · ClinicalTrials.gov registry record
Personalized Postoperative Pain Management Following Thoracic Surgery in Adults
A clinical trial of Thoracic Surgery and Lobectomy, sponsored by OpalGenix.
- Recruiting
- Registry status
- 200
- Enrollment target
- 4
- Study locations
NCT05525923: Recruiting study of Thoracic Surgery and Lobectomy, sponsored by OpalGenix.
NCT05525923 is a study of Thoracic Surgery and Lobectomy that is actively recruiting participants, run by OpalGenix. The registered enrollment target is 200 participants, above the 139-participant average among 5 other Thoracic Surgery trials with a reported enrollment target (44% higher). The trial reports 4 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05525923, a study of Thoracic Surgery and Lobectomy, is actively recruiting participants, sponsored by OpalGenix.
- RECRUITING
- Registry status
- 200 participants
- Enrollment target
- 4
- Study locations
Study Summary
The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone, in adults following thoracic surgery. Major inpatient thoracic surgeries (TS) for lung disease are common and extremely painful surgeries and are associated with sever post-surgical pain, high incidence of chronic post-surgical pain (CPSP), excess opioid use, costly immediate postoperative opioid adverse events (AEs), and long hospital stays. This study is aiming to develop proactive risk prediction algorithms for precision surgical pain relief in adult TS patients through comparison of actual clinical outcomes with standard of care to predicted outcomes based on personalized risk assessments.
Primary Outcome
PONV is measured with a binary yes/no response
Conditions Studied
Study Locations (4)
Pennsylvania
- UPMC Presbyterian Hospital - Pittsburgh
- UPMC Mercy Hospital - Pittsburgh
- UPMC Shadyside Hospital - Pittsburgh
- UPMC Passavant Hospital - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2023-11-30 |
| Est. Completion | 2028-03-01 |
What NCT05525923 shows while recruiting
NCT05525923 is an observational study that tracks outcomes without assigning an intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 139-participant average among 5 other Thoracic Surgery trials with a reported enrollment target (44% higher).
The record links to 4 conditions, with Thoracic Surgery appearing as the primary indexed condition, and to 0 interventions.
NCT05525923 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05525923 about?
NCT05525923 is a clinical study titled "Personalized Postoperative Pain Management Following Thoracic Surgery in Adults". The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone, in adults following thoracic surgery. Major inp...
What is the current status of trial NCT05525923?
This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2023-11-30. Estimated completion is 2028-03-01.
What conditions does trial NCT05525923 study?
This clinical trial studies the following conditions: Thoracic Surgery, Lobectomy, Segmentectomy, Pneumonectomy.
Who is sponsoring clinical trial NCT05525923?
This trial is sponsored by OpalGenix, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05525923 being conducted?
This trial has 4 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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