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NCT05523505 · ClinicalTrials.gov registry record · NA
Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults
A NA study of Reading Disability, sponsored by Vanderbilt University.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05523505: Recruiting NA study of Reading Disability, sponsored by Vanderbilt University.
NCT05523505 is a NA study of Reading Disability that is actively recruiting participants, run by Vanderbilt University. The registered enrollment target is 100 participants, below the 287-participant average among 4 other Reading Disability trials with a reported enrollment target (65% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05523505, a NA study of Reading Disability, is actively recruiting participants, sponsored by Vanderbilt University.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this project is to address the urgent need for effective, scalable adult literacy interventions by integrating breakthroughs in two separate fields: 1.) the brain network science of resilience to reading disorders and 2.) high-definition non-invasive brain network stimulation. This study will first establish the efficacy of a novel, noninvasive stimulation protocol on reading behavior and brain metrics; then will determine how stimulation-induced effects interact with baseline reading comprehension ability; and lastly, will identify whether stimulation-induced effects are more clinically-beneficial than canonical behavioral interventions. Results may change the foundation for how we treat low adult literacy, and have the potential for wider reaching impacts on non-invasive stimulation protocols for other clinical disorders.
Primary Outcome
Stimulation induced change in reading comprehension ability measured by Gates MacGinitie Reading Test: * Reading Comprehension Subtest (Adult Reader; AR): Participants have 35 minutes to read passages and answer 48 comprehension questions about what they read. * Percentile Ranks based on the scores of entering community college students * Primary outcome measure is the change in percentile ranks
Conditions Studied
Interventions
- DEVICE Sham intervention
- DEVICE RLN real non-invasive brain stimulation intervention
- DEVICE RLN and CCN real non-invasive brain stimulation intervention
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2022-11-07 |
| Est. Completion | 2026-09-10 |
| Phase | NA |
What NCT05523505 shows while recruiting
NCT05523505 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 287-participant average among 4 other Reading Disability trials with a reported enrollment target (65% lower).
The record links to 1 condition, with Reading Disability appearing as the primary indexed condition, and to 3 interventions - of which Sham intervention is the first listed.
NCT05523505 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT05523505 about?
NCT05523505 is a clinical study titled "Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults". The goal of this project is to address the urgent need for effective, scalable adult literacy interventions by integrating breakthroughs in two separate fields: 1.) the brain network science of resilience to reading disorders and 2.) high-definition non-invasive brain network stimulation. This study...
What is the current status of trial NCT05523505?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2022-11-07. Estimated completion is 2026-09-10.
What conditions does trial NCT05523505 study?
This clinical trial studies the following conditions: Reading Disability.
What interventions are being tested in trial NCT05523505?
The interventions under investigation include: Sham intervention (DEVICE), RLN real non-invasive brain stimulation intervention (DEVICE), RLN and CCN real non-invasive brain stimulation intervention (DEVICE).
Who is sponsoring clinical trial NCT05523505?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05523505 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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