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NCT05511480 · ClinicalTrials.gov registry record · NA
Reshaping the Motor Engram - An Online Crowdsourcing Study.
A NA study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- NA
- Development phase
- 404
- Enrollment target
NCT05511480: Completed NA study, sponsored by Medical University of South Carolina.
NCT05511480 is a NA study that has completed, run by Medical University of South Carolina. The registered enrollment target is 404 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05511480, a NA study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- NA
- Development phase
- 404 participants
- Enrollment target
Study Summary
A critical point in learning and memory research is whether memories, once consolidated, remain unchanged or whether they continue to undergo plastic changes and remodeling. While previous research has focused on experimental destabilization during early stages of the memory life cycle, i.e., during encoding or early consolidation, experimental data that provides information about the effect of destabilization interventions on well-consolidated memories is still missing. This is particularly true for the procedural memory domain, such as learning a sensorimotor skill. This project is designed to characterize the effect of a single behavioral interference intervention on a previously consolidated sensorimotor skill in a large sample of healthy volunteers recruited through an online crowdsourcing platform. In a longitudinal design, participants will perform an implicit sequence learning task over five consecutive sessions, followed by an interference intervention in session six and a follow-up evaluation of the stability of the learned skill in session seven. The experimental design includes two levels of sequential information (spatial and temporal), which allows the testing of the specificity of the interference intervention. Behavioral performance throughout the experimental sessions is acquired via the manual input on the participants' computer keyboards and used to extract the learning rate and the interference effect (primary outcome).
Primary Outcome
Performance in the learning task is derived from the precision of timing of key presses relative to the occurrence and duration of visual cues presented on the computer screen. The interference rate is operationalized as the change in performance precision over time. The immediate interference effect is analyzed based on the change in performance from before (pre-interference) the interference intervention to directly after the interference intervention in session six (post-interference). This
Interventions
- BEHAVIORAL Interference through learning of a competing motor skill.
- BEHAVIORAL No interference
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 404 participants |
| Start Date | 2022-08-01 |
| Est. Completion | 2023-06-30 |
| Phase | NA |
What the finished NCT05511480 record still lists
NCT05511480 is an interventional study that assigns participants to a tested intervention. The registered 404 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (71% lower).
The record links to 0 conditions, and to 2 interventions - of which Interference through learning of a competing motor skill. is the first listed.
NCT05511480 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05511480 about?
NCT05511480 is a clinical study titled "Reshaping the Motor Engram - An Online Crowdsourcing Study.". A critical point in learning and memory research is whether memories, once consolidated, remain unchanged or whether they continue to undergo plastic changes and remodeling. While previous research has focused on experimental destabilization during early stages of the memory life cycle, i.e., during...
What is the current status of trial NCT05511480?
This trial is currently completed. It is a NA study. The enrollment target is 404 participants. The study started on 2022-08-01. Estimated completion is 2023-06-30.
What interventions are being tested in trial NCT05511480?
The interventions under investigation include: Interference through learning of a competing motor skill. (BEHAVIORAL), No interference (BEHAVIORAL).
Who is sponsoring clinical trial NCT05511480?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05511480's enrollment target sits among peer trials
404 244th of 2000 higher than 1,757 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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