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NCT05505669 · ClinicalTrials.gov registry record

Circulating Biomarkers in the Development of Type 1 Diabetes

A clinical trial of Diabetes, sponsored by City of Hope Medical Center.

Recruiting
Registry status
165
Enrollment target
1
Study location

NCT05505669: Recruiting study of Diabetes, sponsored by City of Hope Medical Center.

NCT05505669 is a study of Diabetes that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 165 participants, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05505669, a study of Diabetes, is actively recruiting participants, sponsored by City of Hope Medical Center.

RECRUITING
Registry status
165 participants
Enrollment target
1
Study location

Study Summary

More than 100 million U.S. adults are now living with diabetes or prediabetes. Investigators still do not fully understand how diabetes develops and how the disease worsens. Insulin is a hormone that helps the body use sugar as a fuel and control blood-sugar levels. People with diabetes have problems making insulin. This is because their insulin-producing beta cells -in the pancreas-are damaged or destroyed. A biomarker is a biological molecule (such as DNA, RNA (the genetic material of cells) or protein) that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker can be measured and found in blood and/or other body fluids (such as saliva and urine). Understanding the biology of beta cells could help find diabetes-related biomarkers. The discoveries from this research could help with early diagnosis of diabetes and lead to the creation of therapies for treating diabetes.

Primary Outcome

The measure will be changes in beta cell death.

Conditions Studied

Interventions

  • OTHER One-time blood (up to 100 ml) will be drawn and the amount of blood drawn is based on weight. Saliva and urine will be collected during the blood draw visit.

Study Locations (1)

California

  • City of Hope Medical Center - Duarte

Trial Details

FieldValue
Enrollment Target 165 participants
Start Date 2022-03-29
Est. Completion 2026-06-09
City of Hope Medical Center

582 total trials

What NCT05505669 shows while recruiting

NCT05505669 is an observational study that tracks outcomes without assigning an intervention. The registered 165 participants enrollment target is mid-sized for trials with a published cap, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (95% lower).

The record links to 1 condition, with Diabetes appearing as the primary indexed condition, and to 1 intervention - of which One-time blood (up to 100 ml) will be drawn and the amount of blood drawn is based on weight. Saliva and urine will be collected during the blood draw visit. is the first listed.

NCT05505669 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT05505669 about?

NCT05505669 is a clinical study titled "Circulating Biomarkers in the Development of Type 1 Diabetes". More than 100 million U.S. adults are now living with diabetes or prediabetes. Investigators still do not fully understand how diabetes develops and how the disease worsens. Insulin is a hormone that helps the body use sugar as a fuel and control blood-sugar levels. People with diabetes have problem...

What is the current status of trial NCT05505669?

This trial is currently recruiting. The enrollment target is 165 participants. The study started on 2022-03-29. Estimated completion is 2026-06-09.

What conditions does trial NCT05505669 study?

This clinical trial studies the following conditions: Diabetes.

What interventions are being tested in trial NCT05505669?

The interventions under investigation include: One-time blood (up to 100 ml) will be drawn and the amount of blood drawn is based on weight. Saliva and urine will be collected during the blood draw visit. (OTHER).

Who is sponsoring clinical trial NCT05505669?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05505669 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Diabetes

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05505669's enrollment target sits among peer trials

165 160th of 338 higher than 179 of 338 other Diabetes trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05505669, the US trial registry maintained by the National Library of Medicine. NCT05505669 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.