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NCT05477875 · ClinicalTrials.gov registry record · Phase 2
Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control
A Phase 2 study of Myopia and Hyperopia, sponsored by University of Florida.
- Completed
- Registry status
- Phase 2
- Development phase
- 35
- Enrollment target
- 1
- Study location
NCT05477875: Completed Phase 2 study of Myopia and Hyperopia, sponsored by University of Florida.
NCT05477875 is a Phase 2 study of Myopia and Hyperopia that has completed, run by University of Florida. The registered enrollment target is 35 participants, below the 268-participant average among 90 other Myopia trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05477875, a Phase 2 study of Myopia and Hyperopia, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
Photorefractive Keratectomy (PRK) is a commonly performed corneal refractive surgery but has significant post-operative pain. Pain medications after PRK are typically opioid-acetaminophen combinations. Alternatives to opioid medication are worth consideration. Patients will receive PRK in each eye sequentially, using the cannabinoid or codeine/acetaminophen for one eye and the other treatment for the fellow eye two weeks later.
Primary Outcome
The Wong-Baker Faces Pain Rating Scale is a pain scale that was developed by Donna Wong and Connie Baker. The scale shows a series of faces ranging from a happy face at 0, or "no hurt", to a crying face at 10, which represents "hurts like the worst pain imaginable"
Conditions Studied
Interventions
- DRUG oral cannabinoid
- COMBINATION_PRODUCT oral codeine/acetaminophen
Study Locations (1)
Florida
- University of Florida Oaks Eye Center - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2024-02-01 |
| Est. Completion | 2025-01-22 |
| Phase | Phase 2 |
What the finished NCT05477875 record still lists
NCT05477875 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 268-participant average among 90 other Myopia trials with a reported enrollment target (87% lower).
The record links to 3 conditions, with Myopia appearing as the primary indexed condition, and to 2 interventions - of which oral cannabinoid is the first listed.
NCT05477875 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT05477875 about?
NCT05477875 is a clinical study titled "Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control". Photorefractive Keratectomy (PRK) is a commonly performed corneal refractive surgery but has significant post-operative pain. Pain medications after PRK are typically opioid-acetaminophen combinations. Alternatives to opioid medication are worth consideration. Patients will receive PRK in each eye s...
What is the current status of trial NCT05477875?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 35 participants. The study started on 2024-02-01. Estimated completion is 2025-01-22.
What conditions does trial NCT05477875 study?
This clinical trial studies the following conditions: Myopia, Hyperopia, Photorefractive Keratectomy.
What interventions are being tested in trial NCT05477875?
The interventions under investigation include: oral cannabinoid (DRUG), oral codeine/acetaminophen (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT05477875?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05477875 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05477875's enrollment target sits among peer trials
35 81st of 90 higher than 9 of 90 other Myopia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Myopia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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