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NCT05466890 · ClinicalTrials.gov registry record · Phase 2
Phase 2a to Evaluate PL-8177 in Subjects with Active Ulcerative Colitis (UC)
A Phase 2 study of Ulcerative Colitis and Ulcerative Colitis Acute, sponsored by Palatin Technologies.
- Active
- Registry status
- Phase 2
- Development phase
- 16
- Enrollment target
- 14
- Study locations
NCT05466890 is a Phase 2 study of Ulcerative Colitis and Ulcerative Colitis Acute that is active but no longer recruiting, run by Palatin Technologies. The registered enrollment target is 16 participants, below the 2,057-participant average among 122 other Ulcerative Colitis trials with a reported enrollment target (99% lower). The trial reports 14 study locations across 8 states.
The verdict
NCT05466890, a Phase 2 study of Ulcerative Colitis and Ulcerative Colitis Acute, is active but no longer recruiting, sponsored by Palatin Technologies.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 16 participants
- Enrollment target
- 14
- Study locations
Study Summary
The purpose of this study is to compare PL8177 (a melanocortin receptor agonist) to placebo (in a 3:1 ratio-meaning that for every 3 people that get the active drug, one will receive placebo). The study treatment will be for 8 weeks. The study will measure safety and the body's ability to handle PL8177 and look at the improvement and healing of the intestine after 8 weeks of treatment. The study will include adult males and nonpregnant, nonlactating females with acute Ulcerative Colitis (UC).
Conditions Studied
Interventions
- DRUG PL8177 Placebo
- DRUG PL8177
Study Locations (14)
Florida
- Advanced Research LLC - Coral Springs
- IHS Health Research/Gastro Health - Kissimmee
- Orlando Health, Inc. - Orlando
New Jersey
- Allied Health Clinical Research Organization, LLC - Englewood - Englewood
- Allied Digestive Health LLC - Freehold
- Allied Health Clinical Research Organization, LLC - Jackson
California
- Gastro Care Institute - Lancaster
- Valiance Clinical Research - Tarzana
Louisiana
- Gastroenterology Clinic of Acadiana - Lafayette
- Delta Research Partners - Monroe
Arizona
- Del Sol Research Management, LLC - Tucson
Kansas
- Kansas Gastroenterology - Wichita
New York
- Weill Cornell Medicine - Jill Roberts Center for Inflammatory Bowel Disease - New York
Pennsylvania
- UPMC Presbyterian - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2022-09-15 |
| Est. Completion | 2025-03-31 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05466890
The ClinicalTrials.gov registry entry for NCT05466890 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,057-participant average among 122 other Ulcerative Colitis trials with a reported enrollment target (99% lower). The listed sponsor is Palatin Technologies, which has 9 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Ulcerative Colitis appearing as the primary indexed condition, and to 2 interventions - of which PL8177 Placebo is the first listed.
NCT05466890 reports 14 study locations spanning 8 distinct geographic areas - top geographies include Florida, New Jersey, California.
Frequently Asked Questions
What is clinical trial NCT05466890 about?
NCT05466890 is a clinical study titled "Phase 2a to Evaluate PL-8177 in Subjects with Active Ulcerative Colitis (UC)". The purpose of this study is to compare PL8177 (a melanocortin receptor agonist) to placebo (in a 3:1 ratio-meaning that for every 3 people that get the active drug, one will receive placebo). The study treatment will be for 8 weeks. The study will measure safety and the body's ability to handle PL8...
What is the current status of trial NCT05466890?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 16 participants. The study started on 2022-09-15. Estimated completion is 2025-03-31.
What conditions does trial NCT05466890 study?
This clinical trial studies the following conditions: Ulcerative Colitis, Ulcerative Colitis Acute, Ulcerative, Ulcerative Colitis Flare.
What interventions are being tested in trial NCT05466890?
The interventions under investigation include: PL8177 Placebo (DRUG), PL8177 (DRUG).
Who is sponsoring clinical trial NCT05466890?
This trial is sponsored by Palatin Technologies, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05466890 being conducted?
This trial has 14 study locations across Arizona, California, Florida, Kansas, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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