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NCT05456035 · ClinicalTrials.gov registry record · NA
CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth
A NA study of Depression, sponsored by Vanderbilt University.
- Recruiting
- Registry status
- NA
- Development phase
- 82
- Enrollment target
- 1
- Study location
NCT05456035: Recruiting NA study of Depression, sponsored by Vanderbilt University.
NCT05456035 is a NA study of Depression that is actively recruiting participants, run by Vanderbilt University. The registered enrollment target is 82 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05456035, a NA study of Depression, is actively recruiting participants, sponsored by Vanderbilt University.
- RECRUITING
- Registry status
- NA
- Development phase
- 82 participants
- Enrollment target
- 1
- Study location
Study Summary
Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of depression in youth more efficient and effective. Participants in the R33 (N=82) will be youth between ages 13- through 17-years-old currently experiencing depression. Youth will be randomized to either an enhanced CBT intervention that teaches social cognitive skills, particularly social perspective taking and theory of mind (CBTSCT) as compared to CBT only. The primary target is improvement in both social cognitive skills and depressive symptoms at post-treatment and at a 6-month follow-up.
Primary Outcome
Faux Pas Recognition test (FPRT) measures the ability to identify and explain faux pas situations where a character unintentionally insults another person due to lack of knowledge about some key feature of the other character. FPRT contains 8 Faux Pas and 8 control stories without a faux pas. Stories are followed by 8 questions. Higher scores mean better theory of mind.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive behavioral therapy plus social cognitive training (CBTSCT)
Study Locations (1)
Tennessee
- Judy Garber - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2022-10-10 |
| Est. Completion | 2026-08 |
| Phase | NA |
What NCT05456035 shows while recruiting
NCT05456035 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 82 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Cognitive behavioral therapy plus social cognitive training (CBTSCT) is the first listed.
NCT05456035 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT05456035 about?
NCT05456035 is a clinical study titled "CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth". Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of...
What is the current status of trial NCT05456035?
This trial is currently recruiting. It is a NA study. The enrollment target is 82 participants. The study started on 2022-10-10. Estimated completion is 2026-08.
What conditions does trial NCT05456035 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT05456035?
The interventions under investigation include: Cognitive behavioral therapy plus social cognitive training (CBTSCT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05456035?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05456035 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05456035's enrollment target sits among peer trials
82 370th of 679 higher than 309 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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