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NCT05437809 · ClinicalTrials.gov registry record · NA
Biobehavioral Reward Responses Associated With Consumption of Nutritionally Diverse Ultra-Processed Foods
A NA study of Obesity and Overeating, sponsored by Oregon Research Institute.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT05437809: Recruiting NA study of Obesity and Overeating, sponsored by Oregon Research Institute.
NCT05437809 is a NA study of Obesity and Overeating that is actively recruiting participants, run by Oregon Research Institute. The registered enrollment target is 50 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05437809, a NA study of Obesity and Overeating, is actively recruiting participants, sponsored by Oregon Research Institute.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The changing food environment, with increasingly abundant ultra-processed food (UPF) options, may directly contribute to rising rates of obesity, though it is unknown which ingredients in UPF elevate their reinforcing nature in a way that may lead to overconsumption. The proposed study is the first to systematically examine differences in the rewarding characteristics of and physiological and metabolic responses to UPFs that are high in fat, refined carbohydrates (like sugar), or both. Understanding the biobehavioral underpinnings that enhance the reinforcing potential of ingredients in UPF (e.g., fat vs. refined carbohydrates) can inform novel intervention targets for the treatment of overeating and obesity.
Primary Outcome
Indicators of subjective reward (craving, palatability, hedonic hunger, and mood) will be assessed by participants' self-reports before, during, and after consumption of the test snack at each of the four food consumption appointments. Each facet of subjective reward will be assessed by 100-point visual analog scales ranging from 0-100.
Conditions Studied
Interventions
- OTHER Intake of nutritionally diverse ultra-processed foods
Study Locations (1)
Pennsylvania
- Drexel University - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-02-20 |
| Est. Completion | 2027-03-31 |
| Phase | NA |
What NCT05437809 shows while recruiting
NCT05437809 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (94% lower).
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Intake of nutritionally diverse ultra-processed foods is the first listed.
NCT05437809 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05437809 about?
NCT05437809 is a clinical study titled "Biobehavioral Reward Responses Associated With Consumption of Nutritionally Diverse Ultra-Processed Foods". The changing food environment, with increasingly abundant ultra-processed food (UPF) options, may directly contribute to rising rates of obesity, though it is unknown which ingredients in UPF elevate their reinforcing nature in a way that may lead to overconsumption. The proposed study is the first ...
What is the current status of trial NCT05437809?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2023-02-20. Estimated completion is 2027-03-31.
What conditions does trial NCT05437809 study?
This clinical trial studies the following conditions: Obesity, Overeating, Food Addiction.
What interventions are being tested in trial NCT05437809?
The interventions under investigation include: Intake of nutritionally diverse ultra-processed foods (OTHER).
Who is sponsoring clinical trial NCT05437809?
This trial is sponsored by Oregon Research Institute, which has 62 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05437809 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05437809's enrollment target sits among peer trials
50 714th of 1053 higher than 324 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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