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NCT05418049 · ClinicalTrials.gov registry record · Phase 2

Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge

A Phase 2 study of Fragile X Syndrome, sponsored by Children's Hospital Medical Center, Cincinnati.

Active
Registry status
Phase 2
Development phase
45
Enrollment target
1
Study location

NCT05418049 is a Phase 2 study of Fragile X Syndrome that is active but no longer recruiting, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 45 participants, below the 99-participant average among 16 other Fragile X Syndrome trials with a reported enrollment target (55% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05418049, a Phase 2 study of Fragile X Syndrome, is active but no longer recruiting, sponsored by Children's Hospital Medical Center, Cincinnati.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
45 participants
Enrollment target
1
Study location

Study Summary

The aim of this study is to utilize neurophysiologic assessments, behavioral measures and clinical measures to assess how much deficits associated with Fragile X Syndrome from pre-dose to post-dose using pharmacology.

Conditions Studied

Fragile X Syndrome

Interventions

  • DRUG Placebo
  • DRUG Roflumilast
  • DRUG Memantine
  • DRUG Baclofen

Study Locations (1)

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2022-09-08
Est. Completion 2026-03-05
Phase Phase 2

Sponsor

Children's Hospital Medical Center, Cincinnati

571 total trials

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What the Registry Record Tells You About NCT05418049

The ClinicalTrials.gov registry entry for NCT05418049 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 99-participant average among 16 other Fragile X Syndrome trials with a reported enrollment target (55% lower). The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 571 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Fragile X Syndrome appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT05418049 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT05418049 about?

NCT05418049 is a clinical study titled "Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge". The aim of this study is to utilize neurophysiologic assessments, behavioral measures and clinical measures to assess how much deficits associated with Fragile X Syndrome from pre-dose to post-dose using pharmacology.

What is the current status of trial NCT05418049?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 2022-09-08. Estimated completion is 2026-03-05.

What conditions does trial NCT05418049 study?

This clinical trial studies the following conditions: Fragile X Syndrome.

What interventions are being tested in trial NCT05418049?

The interventions under investigation include: Placebo (DRUG), Roflumilast (DRUG), Memantine (DRUG), Baclofen (DRUG).

Who is sponsoring clinical trial NCT05418049?

This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05418049 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.