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NCT05411718 · ClinicalTrials.gov registry record · Phase 2

A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome

A Phase 2 study of Colorectal Cancer and Lynch Syndrome, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
40
Enrollment target
1
Study location

NCT05411718 is a Phase 2 study of Colorectal Cancer and Lynch Syndrome that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 40 participants, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05411718, a Phase 2 study of Colorectal Cancer and Lynch Syndrome, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

To learn about the effects of naproxen and aspirin on the normal colon in people with Lynch Syndrome.

Interventions

  • DRUG Aspirin
  • DRUG Naproxen

Study Locations (1)

Texas

  • MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2023-03-21
Est. Completion 2026-11-30
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT05411718

The ClinicalTrials.gov registry entry for NCT05411718 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (97% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 2 interventions - of which Aspirin is the first listed.

NCT05411718 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05411718 about?

NCT05411718 is a clinical study titled "A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome". To learn about the effects of naproxen and aspirin on the normal colon in people with Lynch Syndrome.

What is the current status of trial NCT05411718?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2023-03-21. Estimated completion is 2026-11-30.

What conditions does trial NCT05411718 study?

This clinical trial studies the following conditions: Colorectal Cancer, Lynch Syndrome, T Cells.

What interventions are being tested in trial NCT05411718?

The interventions under investigation include: Aspirin (DRUG), Naproxen (DRUG).

Who is sponsoring clinical trial NCT05411718?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05411718 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.