Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05411484 · ClinicalTrials.gov registry record · Phase 2
Investigation of Laser Assisted Drug Delivery of NanoDOX®
A Phase 2 study of Wounds and Injury, sponsored by Massachusetts General Hospital.
- Active
- Registry status
- Phase 2
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT05411484 is a Phase 2 study of Wounds and Injury that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 10 participants, below the 1,405-participant average among 6 other Wounds and Injury trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05411484, a Phase 2 study of Wounds and Injury, is active but no longer recruiting, sponsored by Massachusetts General Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a self-controlled single-site study of healthy subjects receiving an ablative fractional CO2 (carbon dioxide) laser procedure followed by topical application of NanoDOX® Hydrogel (1% doxycycline). The study includes skin biopsies to evaluate the effects of NanoDOX® Doxycycline Monohydrate Gel on wound healing after the ablative laser procedure. Study subjects will be asked to do 2 visits of 4 hours in total over approximately 1 week. An optional third visit will take place approximately 6 weeks after Visit 1. In this study, 20 subjects are expected to enroll with a goal of 12 healthy subjects to enroll and complete the study.
Conditions Studied
Interventions
- DRUG NanoDOX® Hydrogel
- DEVICE CO2 Ablative Fractional Laser
Study Locations (1)
Massachusetts
- MGH Clinical Unit for Research Trials And Outcome - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2023-11-29 |
| Est. Completion | 2026-04 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05411484
The ClinicalTrials.gov registry entry for NCT05411484 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,405-participant average among 6 other Wounds and Injury trials with a reported enrollment target (99% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Wounds and Injury appearing as the primary indexed condition, and to 2 interventions - of which NanoDOX® Hydrogel is the first listed.
NCT05411484 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05411484 about?
NCT05411484 is a clinical study titled "Investigation of Laser Assisted Drug Delivery of NanoDOX®". This is a self-controlled single-site study of healthy subjects receiving an ablative fractional CO2 (carbon dioxide) laser procedure followed by topical application of NanoDOX® Hydrogel (1% doxycycline). The study includes skin biopsies to evaluate the effects of NanoDOX® Doxycycline Monohydrate Ge...
What is the current status of trial NCT05411484?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 2023-11-29. Estimated completion is 2026-04.
What conditions does trial NCT05411484 study?
This clinical trial studies the following conditions: Wounds and Injury.
What interventions are being tested in trial NCT05411484?
The interventions under investigation include: NanoDOX® Hydrogel (DRUG), CO2 Ablative Fractional Laser (DEVICE).
Who is sponsoring clinical trial NCT05411484?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05411484 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Wounds and Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
RECRUITING · Phase 2
-
Human Upper Extremity Allotransplantation: F/U Protocol
RECRUITING
-
Strategy to Avoid Excessive Oxygen for Critically Ill Trauma Patients
ACTIVE NOT RECRUITING · Phase 3
-
Strategy to Avoid Excessive Oxygen Using an Autonomous Oxygen Titration Intervention
ACTIVE NOT RECRUITING · NA
-
Strategy to Avoid Excessive Oxygen in Major Burn Patients
ACTIVE NOT RECRUITING · Phase 3
-
The Use of a Platform Wound Device for Reducing Infection
COMPLETED · Phase 4
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.