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COMPLETED NA

Cognitive Enhancement in Depression (The COG-D Study)

NCT05400512 · View on ClinicalTrials.gov ↗

Study Summary

This study will investigate whether transcranial direct current stimulation (tDCS) enhances the effects of computerized cognitive training in older adults with recurrent depression (2 or more lifetime episodes; either current or within past 3 years).

Interventions

  • BEHAVIORAL Cognitive Training
  • DEVICE tDCS (active stimulation)
  • DEVICE tDCS (sham stimulation)

Study Locations (1)

Tennessee

  • Vanderbilt University Medical Center — Nashville

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2023-02-08
Est. Completion 2025-08-18
Phase NA

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05400512

The ClinicalTrials.gov registry entry for NCT05400512 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University Medical Center, which has 695 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Depression appearing as the primary indexed condition, and to 3 interventions — of which Cognitive Training is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05400512 reports 1 study location spanning 1 distinct geographic area — top geographies include Tennessee. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05400512 about?

NCT05400512 is a clinical study titled "Cognitive Enhancement in Depression (The COG-D Study)". This study will investigate whether transcranial direct current stimulation (tDCS) enhances the effects of computerized cognitive training in older adults with recurrent depression (2 or more lifetime episodes; either current or within past 3 years).

What is the current status of trial NCT05400512?

This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2023-02-08. Estimated completion is 2025-08-18.

What conditions does trial NCT05400512 study?

This clinical trial studies the following conditions: Depression, Aging, Cognitive Symptom. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05400512?

The interventions under investigation include: Cognitive Training (BEHAVIORAL), tDCS (active stimulation) (DEVICE), tDCS (sham stimulation) (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05400512?

This trial is sponsored by Vanderbilt University Medical Center, which has 695 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05400512 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial