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NCT05396248 · ClinicalTrials.gov registry record · NA
Improve New Learning and Memory in Individuals With Mild Cognitive Impairment
A NA study of Mild Cognitive Impairment, sponsored by Kessler Foundation.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 2
- Study locations
NCT05396248 is a NA study of Mild Cognitive Impairment that is actively recruiting participants, run by Kessler Foundation. The registered enrollment target is 120 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (91% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT05396248, a NA study of Mild Cognitive Impairment, is actively recruiting participants, sponsored by Kessler Foundation.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 2
- Study locations
Study Summary
The current study is a double-blind, placebo-control randomized clinical trial examining the efficacy of memory retraining in individuals with Mild Cognitive Impairment (MCI). Impairment in higher level cognitive processing, such as new learning and memory, is one of the most common deficits in individuals with MCI and such deficits have been shown to exert significant negative impact on multiple aspects of everyday life, including occupational and social functioning. Despite these findings, few studies have attempted to treat these cognitive deficits in order to improve the everyday functioning of individuals with MCI. Through a small randomized clinical trial, the investigators found that individuals with MCI with documented cognitive impairment show a significant improvement in their memory performance following a treatment protocol designed to facilitate learning. The current proposal will replicate this finding and further evaluate (a) the impact of the treatment on everyday functioning, (b) the long term efficacy of the treatment and (c) the utility of booster sessions in facilitating long-term treatment effects. We will randomly assign older individuals who meet criteria for a diagnosis of amnestic MCI to a memory retraining group or a placebo control group. Both groups will undergo baseline, immediate and long-term follow-up assessment consisting of: (1) a traditional neuropsychological battery, (2) an assessment of global functioning examining the impact of the treatment on daily activities, and (3) functional neuroimaging. This design will allow the investigators to evaluate the efficacy of this particular memory retraining technique in an aMCI population through the assessment of cognitive function via a standard evaluation. In addition, the investigators will be able to draw conclusions regarding the impact of this particular memory remediation program on everyday life from questionnaires completed by the participant and a significant other. Optional enr
Conditions Studied
Interventions
- BEHAVIORAL Memory Retraining Exercises
- BEHAVIORAL Placebo Control Memory Exercises
Study Locations (2)
Michigan
- University of Michigan - Ann Arbor
New Jersey
- Kessler Foundation Research Center - West Orange
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2023-06-28 |
| Est. Completion | 2027-03 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05396248
The ClinicalTrials.gov registry entry for NCT05396248 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (91% lower). The listed sponsor is Kessler Foundation, which has 104 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 2 interventions - of which Memory Retraining Exercises is the first listed.
NCT05396248 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Michigan, New Jersey.
Frequently Asked Questions
What is clinical trial NCT05396248 about?
NCT05396248 is a clinical study titled "Improve New Learning and Memory in Individuals With Mild Cognitive Impairment". The current study is a double-blind, placebo-control randomized clinical trial examining the efficacy of memory retraining in individuals with Mild Cognitive Impairment (MCI). Impairment in higher level cognitive processing, such as new learning and memory, is one of the most common deficits in indi...
What is the current status of trial NCT05396248?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2023-06-28. Estimated completion is 2027-03.
What conditions does trial NCT05396248 study?
This clinical trial studies the following conditions: Mild Cognitive Impairment.
What interventions are being tested in trial NCT05396248?
The interventions under investigation include: Memory Retraining Exercises (BEHAVIORAL), Placebo Control Memory Exercises (BEHAVIORAL).
Who is sponsoring clinical trial NCT05396248?
This trial is sponsored by Kessler Foundation, which has 104 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05396248 being conducted?
This trial has 2 study locations across Michigan, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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