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NCT05377177 · ClinicalTrials.gov registry record · NA
Cortical Inhibition as a Biomarker of Response in a Comparison of Bilateral Versus Unilateral Accelerated Theta Burst Stimulation for Suicidal Ideation in Treatment-Resistant Depression -COMBAT-SI
A NA study of Suicidal Ideation and Treatment-Resistant Depression, sponsored by University of California, San Diego.
- Recruiting
- Registry status
- NA
- Development phase
- 76
- Enrollment target
- 1
- Study location
NCT05377177 is a NA study of Suicidal Ideation and Treatment-Resistant Depression that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 76 participants, below the 267-participant average among 84 other Suicidal Ideation trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05377177, a NA study of Suicidal Ideation and Treatment-Resistant Depression, is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- NA
- Development phase
- 76 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective clinical trial to confirm the effectiveness of bilateral accelerated theta burst stimulation (aTBS) on suicidal ideation (SI), while exploring cortical inhibition measures in this treatment paradigm. In this proposed study, the investigators will evaluate the anti-suicidal effects of bilateral aTBS over the DLPFC compared to accelerated intermittent theta burst stimulation (aiTBS) over the left DLPFC in participants with TRD and SI. Additionally, the investigators aim to identify neurophysiological targets through which bilateral aTBS induces remission of SI in TRD differentially from aiTBS.
Conditions Studied
Interventions
- DEVICE Accelerated Theta Burst Stimulation
Study Locations (1)
California
- UCSD Interventional Psychiatry - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2022-09-02 |
| Est. Completion | 2030-07-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05377177
The ClinicalTrials.gov registry entry for NCT05377177 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 76 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 267-participant average among 84 other Suicidal Ideation trials with a reported enrollment target (72% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Suicidal Ideation appearing as the primary indexed condition, and to 1 intervention - of which Accelerated Theta Burst Stimulation is the first listed.
NCT05377177 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05377177 about?
NCT05377177 is a clinical study titled "Cortical Inhibition as a Biomarker of Response in a Comparison of Bilateral Versus Unilateral Accelerated Theta Burst Stimulation for Suicidal Ideation in Treatment-Resistant Depression -COMBAT-SI". This is a prospective clinical trial to confirm the effectiveness of bilateral accelerated theta burst stimulation (aTBS) on suicidal ideation (SI), while exploring cortical inhibition measures in this treatment paradigm. In this proposed study, the investigators will evaluate the anti-suicidal effe...
What is the current status of trial NCT05377177?
This trial is currently recruiting. It is a NA study. The enrollment target is 76 participants. The study started on 2022-09-02. Estimated completion is 2030-07-30.
What conditions does trial NCT05377177 study?
This clinical trial studies the following conditions: Suicidal Ideation, Treatment-Resistant Depression.
What interventions are being tested in trial NCT05377177?
The interventions under investigation include: Accelerated Theta Burst Stimulation (DEVICE).
Who is sponsoring clinical trial NCT05377177?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05377177 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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