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NCT05372627 · ClinicalTrials.gov registry record
NHLBI-Emory Advanced Cardiac CT Reconstruction
A clinical trial, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Not yet
- Registry status
- 1,000
- Enrollment target
NCT05372627: Clinical Trial study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
NCT05372627 is a clinical trial that has not yet begun recruiting, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 1,000 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05372627 has not yet begun recruiting, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- NOT YET RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
Study Summary
Background: Doctors use computed tomography (CT) to get detailed pictures of the heart. CT uses x-rays to gather raw data. Computers assemble this data to make the images doctors look at. A new computer technique can make higher resolution images from the same CT scans. In this natural history study, researchers will take normal CT images of the heart. They will compare those images to super high-resolution (super high-res) images made with a super-computer. Objective: To improve the quality of heart CT scans by using new methods to create the images. Eligibility: People aged 18 years or older who need a CT scan for heart disease. Design: Participants will have a normal CT scan. A substance will be injected through a tube in their arm. They will lie on a table in a large, donut-shaped machine. An X-ray tube will move around their body, taking many pictures. Researchers will use the normal CT scans to create super high-res images. They may do this at the NIH. They may also send the images to the company that made the CT scanner. Participants personal information will be removed before images are sent to the company. The personal information will be replaced by a code. The super high-res images will be returned to the NIH. Some information will be collected from participants medical records. Researchers will compare the normal scans to the super high-res images. Participants' own doctors will also have a chance to see the super high-res images. Participants' CT pictures will be stored and used for future NIH research.
Primary Outcome
The primary endpoint is a semi-quantitative measure of superiority of advanced mathematical image reconstruction compared with standard cardiac CT image reconstruction for study-specific fine detail. Specifically, the endpoint is a Likert-like scale assessing visibility of small structures or fine detail.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2026-07-15 |
| Est. Completion | 2031-01-30 |
What is known before NCT05372627 opens enrollment
NCT05372627 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT05372627 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05372627 about?
NCT05372627 is a clinical study titled "NHLBI-Emory Advanced Cardiac CT Reconstruction". Background: Doctors use computed tomography (CT) to get detailed pictures of the heart. CT uses x-rays to gather raw data. Computers assemble this data to make the images doctors look at. A new computer technique can make higher resolution images from the same CT scans. In this natural history stud...
What is the current status of trial NCT05372627?
This trial is currently not yet recruiting. The enrollment target is 1,000 participants. The study started on 2026-07-15. Estimated completion is 2031-01-30.
Who is sponsoring clinical trial NCT05372627?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
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