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NCT05317689 · ClinicalTrials.gov registry record · Phase 1
Comparing the Effects of Psilocin and Psilocybin in Healthy Adults
A Phase 1 study of Healthy, sponsored by University of California, San Francisco.
- Active
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05317689: Active Phase 1 study of Healthy, sponsored by University of California, San Francisco.
NCT05317689 is a Phase 1 study of Healthy that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 20 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05317689, a Phase 1 study of Healthy, is active but no longer recruiting, sponsored by University of California, San Francisco.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
To compare the physiological and psychological effects of psilocin taken orally by pill or sublingually by dissolving a tablet under the tongue to those of psilocybin taken by pill in healthy adults.
Primary Outcome
blood pressure
Conditions Studied
Interventions
- DRUG Psilocybin
- DRUG Psilocin
- DRUG Sublingual Psilocin
Study Locations (1)
California
- University of California, San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-05-26 |
| Est. Completion | 2025-07 |
| Phase | Phase 1 |
What the registry record for NCT05317689 still lists
NCT05317689 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 3 interventions - of which Psilocybin is the first listed.
NCT05317689 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05317689 about?
NCT05317689 is a clinical study titled "Comparing the Effects of Psilocin and Psilocybin in Healthy Adults". To compare the physiological and psychological effects of psilocin taken orally by pill or sublingually by dissolving a tablet under the tongue to those of psilocybin taken by pill in healthy adults.
What is the current status of trial NCT05317689?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2022-05-26. Estimated completion is 2025-07.
What conditions does trial NCT05317689 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT05317689?
The interventions under investigation include: Psilocybin (DRUG), Psilocin (DRUG), Sublingual Psilocin (DRUG).
Who is sponsoring clinical trial NCT05317689?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05317689 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05317689's enrollment target sits among peer trials
20 861st of 1090 higher than 194 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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