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NCT05285371 · ClinicalTrials.gov registry record · Early Phase 1
Boluses of Ringer's in Surgical Kids (BRiSK Study)
A Early Phase 1 study, sponsored by Children's Hospital of Philadelphia.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 70
- Enrollment target
NCT05285371 is a Early Phase 1 study that has completed, run by Children's Hospital of Philadelphia. The registered enrollment target is 70 participants.
The verdict
NCT05285371, a Early Phase 1 study, has completed, sponsored by Children's Hospital of Philadelphia.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 70 participants
- Enrollment target
Study Summary
Traditional protocols for intravenous fluid administration in children who have undergone a major abdominal or thoracic operation are based on a landmark paper published in 1957 by Holliday and Segar. The basic tenets include: (1) Continuous intravenous fluid administration; (2) Total fluid volume based on the "4:2:1" rule; (3) Use of hypotonic electrolyte solutions, most commonly 0.45% sodium chloride (NaCl) + 20 milliequivalents per liter (mEq/L) potassium chloride (KCl); and (4) Inclusion of 5% dextrose to increase the osmolarity of the infusate and to help prevent ketosis and acidemia.
Interventions
- OTHER Medical Chart Review
- DIAGNOSTIC_TEST Urinalysis (UA)
- DIAGNOSTIC_TEST Complete Metabolic Panel (CMP)
- DIAGNOSTIC_TEST Glucose Stick Test (d-Stick)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2022-02-22 |
| Est. Completion | 2024-08-01 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05285371
The ClinicalTrials.gov registry entry for NCT05285371 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Medical Chart Review is the first listed.
NCT05285371 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05285371 about?
NCT05285371 is a clinical study titled "Boluses of Ringer's in Surgical Kids (BRiSK Study)". Traditional protocols for intravenous fluid administration in children who have undergone a major abdominal or thoracic operation are based on a landmark paper published in 1957 by Holliday and Segar. The basic tenets include: (1) Continuous intravenous fluid administration; (2) Total fluid volume b...
What is the current status of trial NCT05285371?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 70 participants. The study started on 2022-02-22. Estimated completion is 2024-08-01.
What interventions are being tested in trial NCT05285371?
The interventions under investigation include: Medical Chart Review (OTHER), Urinalysis (UA) (DIAGNOSTIC_TEST), Complete Metabolic Panel (CMP) (DIAGNOSTIC_TEST), Glucose Stick Test (d-Stick) (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05285371?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
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