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NCT05241249 · ClinicalTrials.gov registry record · Phase 2

Stimulation With Bethanechol in Combination With Gemcitabine and Nab-paclitaxel in Pancreatic Adenocarcinoma

A Phase 2 study of Pancreas Cancer, sponsored by Susan E. Bates.

Recruiting
Registry status
Phase 2
Development phase
37
Enrollment target
1
Study location

NCT05241249 is a Phase 2 study of Pancreas Cancer that is actively recruiting participants, run by Susan E. Bates. The registered enrollment target is 37 participants, below the 907-participant average among 54 other Pancreas Cancer trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05241249, a Phase 2 study of Pancreas Cancer, is actively recruiting participants, sponsored by Susan E. Bates.

RECRUITING
Registry status
Phase 2
Development phase
37 participants
Enrollment target
1
Study location

Study Summary

The primary objective of this study is to assess the impact of bethanechol therapy on R0 resection rates. The safety objective will be assessment of the safety and tolerability of bethanechol in combination with gemcitabine and nab-paclitaxel. The exploratory objective will be to evaluate genomic biomarkers associated with parasympathetic stimulation in pancreatic cancer, and the ability to reduce tumor growth rate.

Conditions Studied

Interventions

  • DRUG Gemcitabine
  • DRUG Bethanechol
  • DRUG nab-paclitaxel

Study Locations (1)

New York

  • Columbia University Medical Center - New York

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2022-02-01
Est. Completion 2026-01
Phase Phase 2

Sponsor

Susan E. Bates

2 total trials

What the Registry Record Tells You About NCT05241249

The ClinicalTrials.gov registry entry for NCT05241249 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 907-participant average among 54 other Pancreas Cancer trials with a reported enrollment target (96% lower). The listed sponsor is Susan E. Bates, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pancreas Cancer appearing as the primary indexed condition, and to 3 interventions - of which Gemcitabine is the first listed.

NCT05241249 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT05241249 about?

NCT05241249 is a clinical study titled "Stimulation With Bethanechol in Combination With Gemcitabine and Nab-paclitaxel in Pancreatic Adenocarcinoma". The primary objective of this study is to assess the impact of bethanechol therapy on R0 resection rates. The safety objective will be assessment of the safety and tolerability of bethanechol in combination with gemcitabine and nab-paclitaxel. The exploratory objective will be to evaluate genomic bi...

What is the current status of trial NCT05241249?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 37 participants. The study started on 2022-02-01. Estimated completion is 2026-01.

What conditions does trial NCT05241249 study?

This clinical trial studies the following conditions: Pancreas Cancer.

What interventions are being tested in trial NCT05241249?

The interventions under investigation include: Gemcitabine (DRUG), Bethanechol (DRUG), nab-paclitaxel (DRUG).

Who is sponsoring clinical trial NCT05241249?

This trial is sponsored by Susan E. Bates, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05241249 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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