Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05226494 · ClinicalTrials.gov registry record · Phase 1

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

A Phase 1 study of Glioma, Malignant, sponsored by NanoPharmaceuticals.

Recruiting
Registry status
Phase 1
Development phase
34
Enrollment target
1
Study location

NCT05226494 is a Phase 1 study of Glioma, Malignant that is actively recruiting participants, run by NanoPharmaceuticals. The registered enrollment target is 34 participants, below the 62-participant average among 19 other Glioma, Malignant trials with a reported enrollment target (45% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05226494, a Phase 1 study of Glioma, Malignant, is actively recruiting participants, sponsored by NanoPharmaceuticals.

RECRUITING
Registry status
Phase 1
Development phase
34 participants
Enrollment target
1
Study location

Study Summary

Glioblastoma is a highly aggressive and fatal form of primary malignant brain tumor with limited treatment options. fb-PMT affects a large group of cancer cell signaling pathways and thus may be effective in heterogeneous, treatment-resistant tumors such as Glioblastoma. fb-PMT also is actively transported across the blood-brain barrier into the brain. This study is being conducted to determine the dose level for further clinical development of fb-PMT to treat recurrent Glioblastoma.

Conditions Studied

Interventions

  • DRUG fb-PMT

Study Locations (1)

Connecticut

  • Smilow Cancer Hospital - New Haven

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2022-06-23
Est. Completion 2027-10
Phase Phase 1

Sponsor

NanoPharmaceuticals

1 total trials

What the Registry Record Tells You About NCT05226494

The ClinicalTrials.gov registry entry for NCT05226494 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 62-participant average among 19 other Glioma, Malignant trials with a reported enrollment target (45% lower). The listed sponsor is NanoPharmaceuticals, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Glioma, Malignant appearing as the primary indexed condition, and to 1 intervention - of which fb-PMT is the first listed.

NCT05226494 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT05226494 about?

NCT05226494 is a clinical study titled "Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma". Glioblastoma is a highly aggressive and fatal form of primary malignant brain tumor with limited treatment options. fb-PMT affects a large group of cancer cell signaling pathways and thus may be effective in heterogeneous, treatment-resistant tumors such as Glioblastoma. fb-PMT also is actively tran...

What is the current status of trial NCT05226494?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 34 participants. The study started on 2022-06-23. Estimated completion is 2027-10.

What conditions does trial NCT05226494 study?

This clinical trial studies the following conditions: Glioma, Malignant.

What interventions are being tested in trial NCT05226494?

The interventions under investigation include: fb-PMT (DRUG).

Who is sponsoring clinical trial NCT05226494?

This trial is sponsored by NanoPharmaceuticals, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05226494 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Glioma, Malignant

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.