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NCT05221905 · ClinicalTrials.gov registry record · Phase 1

Effects of Inorganic Nitrate and Intensity of Exercise on Cardiovascular Health in Post-Menopausal Females

A Phase 1 study of Arterial Stiffness and Vascular Dilation, sponsored by University of Virginia.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target
1
Study location

NCT05221905 is a Phase 1 study of Arterial Stiffness and Vascular Dilation that has completed, run by University of Virginia. The registered enrollment target is 24 participants, below the 121-participant average among 12 other Arterial Stiffness trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05221905, a Phase 1 study of Arterial Stiffness and Vascular Dilation, has completed, sponsored by University of Virginia.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

Post-menopausal females experience elevated cardiovascular disease risk (CVD), compared to premenopausal females and age-matched males. Current exercise guidelines appear inadequate to ameliorate this increased risk and higher intensity exercise may be necessary. Oral inorganic nitrate supplementation enhances both exercise performance and CVD risk profile in several clinical conditions. However, the effects of this intervention in post-menopausal females is unexplored.

Interventions

  • DRUG BEET IT - Concentrate Beet root juice
  • DRUG BEET IT - Concentrate Beet root juice (nitrate depleted)

Study Locations (1)

Virginia

  • Student Health and Wellness Center - Charlottesville

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2021-11-01
Est. Completion 2023-04-01
Phase Phase 1

Sponsor

University of Virginia

449 total trials

What the Registry Record Tells You About NCT05221905

The ClinicalTrials.gov registry entry for NCT05221905 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 121-participant average among 12 other Arterial Stiffness trials with a reported enrollment target (80% lower). The listed sponsor is University of Virginia, which has 449 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Arterial Stiffness appearing as the primary indexed condition, and to 2 interventions - of which BEET IT - Concentrate Beet root juice is the first listed.

NCT05221905 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.

Frequently Asked Questions

What is clinical trial NCT05221905 about?

NCT05221905 is a clinical study titled "Effects of Inorganic Nitrate and Intensity of Exercise on Cardiovascular Health in Post-Menopausal Females". Post-menopausal females experience elevated cardiovascular disease risk (CVD), compared to premenopausal females and age-matched males. Current exercise guidelines appear inadequate to ameliorate this increased risk and higher intensity exercise may be necessary. Oral inorganic nitrate supplementati...

What is the current status of trial NCT05221905?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2021-11-01. Estimated completion is 2023-04-01.

What conditions does trial NCT05221905 study?

This clinical trial studies the following conditions: Arterial Stiffness, Vascular Dilation.

What interventions are being tested in trial NCT05221905?

The interventions under investigation include: BEET IT - Concentrate Beet root juice (DRUG), BEET IT - Concentrate Beet root juice (nitrate depleted) (DRUG).

Who is sponsoring clinical trial NCT05221905?

This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05221905 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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