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ACTIVE NOT RECRUITING Phase 2

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants With Select B-Cell Malignancies

NCT05207670 · View on ClinicalTrials.gov ↗

Study Summary

This study will evaluate the efficacy, safety, and pharmacokinetics of mosunetuzumab subcutaneous (SC) formulation in participants with selected B-cell malignancies (types of non-Hodgkin's lymphoma \[NHL\]).

Conditions Studied

Interventions

  • DRUG Tocilizumab
  • DRUG Mosunetuzumab (Cohorts A-C)
  • DRUG Mosunetuzumab (Cohorts D-E)

Study Locations (20)

Florida

  • SCRI Florida Cancer Specialists South — Fort Myers
  • Mayo Clinic Jacksonville - PPDS — Jacksonville
  • Cancer Specialists of North Florida - Jacksonville — Jacksonville
  • Florida Cancer Specialists - NORTH - SCRI - PPDS — St. Petersburg
  • Florida Cancer Specialists - EAST - SCRI - PPDS — West Palm Beach

Alabama

  • Infirmary Cancer Care — Mobile

Alaska

  • Alaska Oncology & Hematology, LLC — Anchorage

Arizona

  • Mayo Clinic Arizona — Phoenix

California

  • City of Hope — Duarte

Colorado

  • Rocky Mountain Cancer Centers (Aurora) - USOR — Aurora

Delaware

  • Medical Oncology Hematology Consultants — Newark

Iowa

  • Mission Blood and Cancer - MercyOne Cancer Center — Des Moines

Trial Details

FieldValue
Enrollment Target 320 participants
Start Date 2022-02-01
Est. Completion 2028-07-31
Phase Phase 2

Sponsor

Genentech

206 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05207670

The ClinicalTrials.gov registry entry for NCT05207670 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 320 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 206 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Non-Hodgkin Lymphoma appearing as the primary indexed condition, and to 3 interventions — of which Tocilizumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05207670 reports 20 study locations spanning 16 distinct geographic areas — top geographies include Florida, Alabama, Alaska. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05207670 about?

NCT05207670 is a clinical study titled "A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants With Select B-Cell Malignancies". This study will evaluate the efficacy, safety, and pharmacokinetics of mosunetuzumab subcutaneous (SC) formulation in participants with selected B-cell malignancies (types of non-Hodgkin's lymphoma \[NHL\]).

What is the current status of trial NCT05207670?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 320 participants. The study started on 2022-02-01. Estimated completion is 2028-07-31.

What conditions does trial NCT05207670 study?

This clinical trial studies the following conditions: Non-Hodgkin Lymphoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05207670?

The interventions under investigation include: Tocilizumab (DRUG), Mosunetuzumab (Cohorts A-C) (DRUG), Mosunetuzumab (Cohorts D-E) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05207670?

This trial is sponsored by Genentech, which has 206 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05207670 being conducted?

This trial has 20 study locations across Alabama, Alaska, Arizona, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial