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The PATHway Study: Primary Care Based Depression Prevention in Adolescents
NCT05203198 · View on ClinicalTrials.gov ↗
Study Summary
Prevention of depressive disorders has become a key priority for the NIMH, but the investigators have no widely available public health strategy to reduce morbidity and mortality. To address this need, the investigators developed and evaluated the primary care based-technology "behavioral vaccine," Competent Adulthood Transition with Cognitive-Behavioral Humanistic and Interpersonal Therapy (CATCH-IT). The investigators will engage N=4 health systems representative of the United States health care system, and conduct a factorial design study to optimize the intervention in preparation for an implementation study and eventual dissemination.
Conditions Studied
Interventions
- BEHAVIORAL Competent Adulthood Transition with Cognitive-Behavioral, Humanistic and Interpersonal Training
Study Locations (6)
Illinois
- Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago
- UI Health — Chicago
- University of Chicago Comer Children's Hospital — Chicago
- Northshore University HealthSystem — Glenview
- Advocate Aurora Health — Park Ridge
Texas
- UT Southwestern Medical Center — Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2022-02-01 |
| Est. Completion | 2026-10-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05203198
The ClinicalTrials.gov registry entry for NCT05203198 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Illinois at Chicago, which has 421 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention — of which Competent Adulthood Transition with Cognitive-Behavioral, Humanistic and Interpersonal Training is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05203198 reports 6 study locations spanning 2 distinct geographic areas — top geographies include Illinois, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05203198 about?
NCT05203198 is a clinical study titled "The PATHway Study: Primary Care Based Depression Prevention in Adolescents". Prevention of depressive disorders has become a key priority for the NIMH, but the investigators have no widely available public health strategy to reduce morbidity and mortality. To address this need, the investigators developed and evaluated the primary care based-technology "behavioral vaccine," ...
What is the current status of trial NCT05203198?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 400 participants. The study started on 2022-02-01. Estimated completion is 2026-10-31.
What conditions does trial NCT05203198 study?
This clinical trial studies the following conditions: Depression, Mental Disorder in Adolescence. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05203198?
The interventions under investigation include: Competent Adulthood Transition with Cognitive-Behavioral, Humanistic and Interpersonal Training (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05203198?
This trial is sponsored by University of Illinois at Chicago, which has 421 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05203198 being conducted?
This trial has 6 study locations across Illinois, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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