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NCT05202145 · ClinicalTrials.gov registry record · Phase 1

Drug-Drug Interaction (DDI) Study of ALXN2050 in Healthy Adult Participants

A Phase 1 study of Healthy, sponsored by Alexion Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
61
Enrollment target
1
Study location

NCT05202145: Completed Phase 1 study of Healthy, sponsored by Alexion Pharmaceuticals.

NCT05202145 is a Phase 1 study of Healthy that has completed, run by Alexion Pharmaceuticals. The registered enrollment target is 61 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05202145, a Phase 1 study of Healthy, has completed, sponsored by Alexion Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
61 participants
Enrollment target
1
Study location

Study Summary

This study will evaluate the potential drug interactions between ALXN2050 and cyclosporine (Part 1), between ALXN2050 and tacrolimus (Part 2), and between ALXN2050 and mycophenolate mofetil (MMF) (Part 3).

Conditions Studied

Interventions

  • DRUG Tacrolimus
  • DRUG Cyclosporine
  • DRUG MMF
  • DRUG ALXN2050

Study Locations (1)

Arizona

  • Clinical Study Site - Tempe

Trial Details

FieldValue
Enrollment Target 61 participants
Start Date 2022-01-11
Est. Completion 2022-03-21
Phase Phase 1
Alexion Pharmaceuticals

162 total trials

What the finished NCT05202145 record still lists

NCT05202145 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower).

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 4 interventions - of which Tacrolimus is the first listed.

NCT05202145 reports a single indexed study location in Arizona.

Frequently Asked Questions

What is clinical trial NCT05202145 about?

NCT05202145 is a clinical study titled "Drug-Drug Interaction (DDI) Study of ALXN2050 in Healthy Adult Participants". This study will evaluate the potential drug interactions between ALXN2050 and cyclosporine (Part 1), between ALXN2050 and tacrolimus (Part 2), and between ALXN2050 and mycophenolate mofetil (MMF) (Part 3).

What is the current status of trial NCT05202145?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 61 participants. The study started on 2022-01-11. Estimated completion is 2022-03-21.

What conditions does trial NCT05202145 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT05202145?

The interventions under investigation include: Tacrolimus (DRUG), Cyclosporine (DRUG), MMF (DRUG), ALXN2050 (DRUG).

Who is sponsoring clinical trial NCT05202145?

This trial is sponsored by Alexion Pharmaceuticals, which has 162 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05202145 being conducted?

This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05202145's enrollment target sits among peer trials

61 364th of 1090 higher than 723 of 1,090 other Healthy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05202145, the US trial registry maintained by the National Library of Medicine. NCT05202145 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.