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ACTIVE NOT RECRUITING Phase 2

Neoadjuvant Endocrine Therapy in ER-positive, HER2-negative Early Stage Breast Cancer

NCT05150652 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this study is to access whether treatment of early state estrogen-rich breast cancers with neoadjuvant endocrine therapy will result in higher rates of margin negativity on lumpectomy specimen.

Interventions

  • DRUG Tamoxifen
  • DRUG Letrozole 2.5mg
  • DRUG Anastrozole 1mg
  • DRUG Exemestane 25 mg

Study Locations (1)

Kentucky

  • University of Kentucky Markey Cancer Center — Lexington

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2022-02-18
Est. Completion 2026-06-09
Phase Phase 2

Sponsor

Irada Ibrahim-zada

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05150652

The ClinicalTrials.gov registry entry for NCT05150652 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Irada Ibrahim-zada, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Breast Cancer appearing as the primary indexed condition, and to 4 interventions — of which Tamoxifen is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05150652 reports 1 study location spanning 1 distinct geographic area — top geographies include Kentucky. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05150652 about?

NCT05150652 is a clinical study titled "Neoadjuvant Endocrine Therapy in ER-positive, HER2-negative Early Stage Breast Cancer". The goal of this study is to access whether treatment of early state estrogen-rich breast cancers with neoadjuvant endocrine therapy will result in higher rates of margin negativity on lumpectomy specimen.

What is the current status of trial NCT05150652?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2022-02-18. Estimated completion is 2026-06-09.

What conditions does trial NCT05150652 study?

This clinical trial studies the following conditions: Breast Cancer, Breast Carcinoma, HER2-negative Breast Cancer, Node-negative Breast Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05150652?

The interventions under investigation include: Tamoxifen (DRUG), Letrozole 2.5mg (DRUG), Anastrozole 1mg (DRUG), Exemestane 25 mg (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05150652?

This trial is sponsored by Irada Ibrahim-zada, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05150652 being conducted?

This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial