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NCT05147220 · ClinicalTrials.gov registry record · Phase 3
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)
A Phase 3 study of Relapsing Multiple Sclerosis, sponsored by Novartis Pharmaceuticals.
- Active
- Registry status
- Phase 3
- Development phase
- 1,001
- Enrollment target
- 20
- Study locations
NCT05147220: Active Phase 3 study of Relapsing Multiple Sclerosis, sponsored by Novartis Pharmaceuticals.
NCT05147220 is a Phase 3 study of Relapsing Multiple Sclerosis that is active but no longer recruiting, run by Novartis Pharmaceuticals. The registered enrollment target is 1,001 participants, below the 2,126-participant average among 23 other Relapsing Multiple Sclerosis trials with a reported enrollment target (53% lower). The trial reports 20 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05147220, a Phase 3 study of Relapsing Multiple Sclerosis, is active but no longer recruiting, sponsored by Novartis Pharmaceuticals.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 1,001 participants
- Enrollment target
- 20
- Study locations
Study Summary
To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)
Primary Outcome
ARR is the average number of confirmed MS relapses in a year
Conditions Studied
Interventions
- DRUG Teriflunomide
- DRUG Remibrutinib
Study Locations (20)
Florida
- Neurology of Central FL Res Ctr - Altamonte Springs
- Arrow Clinical Trials - Daytona Beach
- Homestead Assoc In Research Inc - Homestead
- Reliant Medical Research - Miami
- Neurological Services of Orlando PA - Orlando
- Orlando Health Clinical Trials - Orlando
- Comprehensive Neurology Clinic - Orlando
- Neurology Associates of Ormond Beach - Ormond Beach
California
- The Research and Education Inst. of Alta Bates Summit Med. Grp - Berkeley
- The Neuron Clinic - Chula Vista
- Glendale Adventist Medical Center - Glendale
- Hoag Health System - Newport Beach
- SC3 Research Pasadena - Pasadena
- Neuro Center - Pomona
Arizona
- AZ Integrated Neuro and Spine - Phoenix
- Center for Neurosciences - Tucson
Arkansas
- The Belinga Clinic - Fort Smith
Colorado
- Alpine Clinical Research Center - Boulder
Delaware
- Christiana Care Health Services - Newark
District of Columbia
- Washington Hospital Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,001 participants |
| Start Date | 2021-12-16 |
| Est. Completion | 2030-10-30 |
| Phase | Phase 3 |
What the registry record for NCT05147220 still lists
NCT05147220 is an interventional study that assigns participants to a tested intervention. Its 1,001 participants enrollment target places it among the larger protocols in the corpus, below the 2,126-participant average among 23 other Relapsing Multiple Sclerosis trials with a reported enrollment target (53% lower).
The record links to 1 condition, with Relapsing Multiple Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which Teriflunomide is the first listed.
NCT05147220 names 20 study sites across 7 states, led by Florida, California, Arizona.
Frequently Asked Questions
What is clinical trial NCT05147220 about?
NCT05147220 is a clinical study titled "Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)". To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)
What is the current status of trial NCT05147220?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 1,001 participants. The study started on 2021-12-16. Estimated completion is 2030-10-30.
What conditions does trial NCT05147220 study?
This clinical trial studies the following conditions: Relapsing Multiple Sclerosis.
What interventions are being tested in trial NCT05147220?
The interventions under investigation include: Teriflunomide (DRUG), Remibrutinib (DRUG).
Who is sponsoring clinical trial NCT05147220?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05147220 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Relapsing Multiple Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05147220's enrollment target sits among peer trials
1,001 7th of 23 higher than 17 of 23 other Relapsing Multiple Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Relapsing Multiple Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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